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Current Drug Targets

Editor-in-Chief

ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

New Multidrug Resistance Reversal Agents

Author(s): Masami Kawase and Noboru Motohashi

Volume 4 , Issue 1 , 2003

Page: [31 - 43] Pages: 13

DOI: 10.2174/1389450033347064

Price: $65

Abstract

Multidrug resistance (MDR) to antitumor agents represents a significant challenge to effective chemotherapy. The use of MDR modulators is a promising approach to overcome the undesired MDR phenotype. The more effective MDR modulators are urgently needed for clinical use. This review focuses on literatures published in 1998-2001.

Keywords: Multidrug Resistance, chemotherapy, MDR phenotype, antitumor agents


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