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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

Vaccine Ingredients: Components that Influence Vaccine Efficacy

Author(s): Aneta Kocourkova, Jan Honegr, Kamil Kuca and Jana Danova

Volume 17 , Issue 5 , 2017

Page: [451 - 466] Pages: 16

DOI: 10.2174/1389557516666160801103303

Price: $65


Vaccination is defined as the administration of an antigenic material in order to stimulate the immune system, leading to the development of adaptive immunity to a pathogen. Vaccines can prevent or reduce morbidity from a vast number of infections. This manuscript presents an analysis of vaccine types and vaccine substances, concentrating on individual components including the active ingredient, adjuvants, preservatives, stabilizers, inactivators, antibiotics, diluents and other substances. While many papers have been published on individual vaccine components, this review provides detail on a wide range of the most commonly-used vaccine ingredients and components that have been tested in clinical trials.

Keywords: Active ingredient, adjuvant, antibiotic, inactivator, preservative, stabilizer, vaccination, vaccine.

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