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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy

Author(s): Ariel R. Guerrero, Felipe Oyarzun-Ampuero, Natalia Hassan, Alejandro H. Corvalan, Andrew F.G. Quest and Marcelo J. Kogan

Volume 22 , Issue 39 , 2016

Page: [5988 - 5997] Pages: 10

DOI: 10.2174/1381612822666160712165409

Price: $65


In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths worldwide. This article reviews advances in the treatment of this pathology using several types of nanoparticles. First, we start with an overview of gastric cancer, its prevention, detection and the available treatments. Then, we discuss nanotechnology-based novel strategies using polymeric nanosystems, nanovesicular systems and inorganic nanoparticles. All of these systems are being evaluated in the perspective of improving the targeting of anticancer drugs and reducing their negative side effects.

Keywords: Nanoparticles, nanocarriers, gastric cancer, treatment, drug delivery, targeting.

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