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Current Drug Targets


ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

The Pharmacological Treatment of Cachexia

Author(s): Josep M. Argiles, Vanessa Almendro, Sílvia Busquets and Francisco J. Lopez-Soriano

Volume 5 , Issue 3 , 2004

Page: [265 - 277] Pages: 13

DOI: 10.2174/1389450043490505

Price: $65


Cachexia is a complex syndrome. The main components of this pathological state are anorexia and metabolic abnormalities such as glucose intolerance, fat depletion, and muscle protein catabolism among others. The aim of the present article is to review the different therapeutic approaches that have been designed to fight and counteract muscle wasting in different pathological states such as cancer, AIDS and chronic heart failure.

Keywords: cachexia, cancer, aids, chronic heart failure, anorexia, tumor therapy

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