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Current Molecular Medicine

Editor-in-Chief

ISSN (Print): 1566-5240
ISSN (Online): 1875-5666

Review Article

Small RNAs Play Big Roles: MicroRNAs in Diabetic Wound Healing

Author(s): F. Fahs, X.-L. Bi, F.-S. Yu, L. Zhou and Q.-S. Mi

Volume 16 , Issue 6 , 2016

Page: [545 - 552] Pages: 8

DOI: 10.2174/1566524016666160607091156

Price: $65

Abstract

Skin and corneal wounds in diabetics are a major healthcare burden. MicroRNAs are small, non-coding RNAs that post-transcriptionally regulate the expression of proteincoding genes. Studies have identified microRNAs involved in all phases of wound healing. The dysregulation of microRNAs can contribute to impaired or delayed skin and corneal wound healing in diabetics. Here, we present a comprehensive review of the literature involving microRNAs in diabetic skin and corneal wound healing as well as those serving as potential biomarkers for diabetic wound healing.

Keywords: microRNA, wound healing, skin, cornea, diabetes, pathogenesis.


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