Abstract
Primary liver tumors and liver metastases are the two most common malignant liver tumors. In cases of unresectable malignant tumors, local ablative therapies are considered as the preferred option. These include transarterial chemoembolization, radioembolization, radiofrequency ablation, microwave ablation, percutaneous alcohol injection, cryotherapy and laser therapy. Local ablative therapies have the additive advantage of preserving the uninvolved liver parenchyma, and can be used in combination or as adjuvant to surgery or bridge to liver transplantation. MRI is more sensitive and accurate compared to CT in detecting and characterize malignant liver lesions pre- and post-therapy. The aim of this article is to describe the MRI appearance of post-treatment liver changes after a wide variety of local ablative therapies and discuss some of the new advances in post-treatment liver imaging.
Keywords: Alcohol ablation, locoregional treatment, malignant liver lesions, microwave ablation, MRI, radiofrequency ablation, transarterial chemoembolization, 90Y radioembolization.
Current Cancer Therapy Reviews
Title:Post-locoregional Therapy MRI Evaluation of Malignant Liver Lesions
Volume: 9 Issue: 3
Author(s): Ilaria Santagostino, Mamdoh AlObaidy, Miguel Ramalho, Kyung Sook Shin, Kiran K.R. Busireddy and Richard C. Semelka
Affiliation:
Keywords: Alcohol ablation, locoregional treatment, malignant liver lesions, microwave ablation, MRI, radiofrequency ablation, transarterial chemoembolization, 90Y radioembolization.
Abstract: Primary liver tumors and liver metastases are the two most common malignant liver tumors. In cases of unresectable malignant tumors, local ablative therapies are considered as the preferred option. These include transarterial chemoembolization, radioembolization, radiofrequency ablation, microwave ablation, percutaneous alcohol injection, cryotherapy and laser therapy. Local ablative therapies have the additive advantage of preserving the uninvolved liver parenchyma, and can be used in combination or as adjuvant to surgery or bridge to liver transplantation. MRI is more sensitive and accurate compared to CT in detecting and characterize malignant liver lesions pre- and post-therapy. The aim of this article is to describe the MRI appearance of post-treatment liver changes after a wide variety of local ablative therapies and discuss some of the new advances in post-treatment liver imaging.
Export Options
About this article
Cite this article as:
Santagostino Ilaria, AlObaidy Mamdoh, Ramalho Miguel, Shin Sook Kyung, Busireddy K.R. Kiran and Semelka C. Richard, Post-locoregional Therapy MRI Evaluation of Malignant Liver Lesions, Current Cancer Therapy Reviews 2013; 9 (3) . https://dx.doi.org/10.2174/157339470903140220145116
DOI https://dx.doi.org/10.2174/157339470903140220145116 |
Print ISSN 1573-3947 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6301 |
Call for Papers in Thematic Issues
Current progress in Protein Degradation and Cancer Therapy
argeted Protein Degradation is gaining momentum in cancer therapy, it facilitate targeting undruggable proteins, it overcome cancer resistance and avoid undesirable side effects. Thus small molecules degraders have emerged as novel therapeutic strategy. Targeted protein degradation (TPD), the process of eliminating a protein of interest hold a great promise for ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Vasopressin in Liver Disease – Should We Turn On or Off?
Current Clinical Pharmacology Vascular Biomarkers in Asthma and COPD
Current Topics in Medicinal Chemistry Mitochondria-Targeted Drugs
Current Molecular Pharmacology The Effects of Obesity on the Cerebral Vasculature
Current Vascular Pharmacology Comparative Study of Eudragit RS 100 and RL 100 Nanoparticles as Ophthalmic Vehicle for Fungal Infection
Pharmaceutical Nanotechnology Inflammatory Markers in Essential Hypertension: Potential Clinical Implications
Current Vascular Pharmacology The Vascular Component of Alzheimer`s Disease
Current Neurovascular Research Stable Angina Pectoris: Current Medical Treatment
Current Pharmaceutical Design Combinational Approaches Targeting Neurodegeneration, Oxidative Stress, and Inflammation in the Treatment of Diabetic Retinopathy
Current Drug Targets Nanostructures for Drug Delivery to the Brain
Current Medicinal Chemistry Topiramate in the New Generation of Drugs: Efficacy in the Treatment of Alcoholic Patients
Current Pharmaceutical Design Neuroprotective Effects of Intravenous Anesthetics: A New Critical Perspective
Current Pharmaceutical Design Therapeutic Effects and Mechanisms of Action of Cyclosporine A Ophthalmic Solution in the Treatment of Vernal Keratoconjunctivitis
Current Pharmaceutical Analysis A Current Update on the Use of Alpha Lipoic Acid in the Management of Type 2 Diabetes Mellitus
Endocrine, Metabolic & Immune Disorders - Drug Targets Vascular Effects of Insulin and Their Relation to Endothelial Dysfunction, Insulin Resistance and Hypertension
Current Hypertension Reviews Antihemostatic Strategies of Blood-Feeding Arthropods
Current Drug Targets - Cardiovascular & Hematological Disorders Endothelial Dysfunction and Coronary Artery Spasm
Current Drug Targets - Cardiovascular & Hematological Disorders Fractional Flow Reserve: Physiological Basis, Advantages and Limitations, and Potential Gender Differences
Current Cardiology Reviews Preconditioning and Shear Stress in the Microcirculation in Ischemia-Reperfusion Injury
Current Cardiology Reviews Inflammatory Markers in Hyperlipidemia: From Experimental Models to Clinical Practice
Current Pharmaceutical Design