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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Dendritic Cells in Atherosclerosis

Author(s): Siân P. Cartland and Wendy Jessup

Volume 19 , Issue 33 , 2013

Page: [5883 - 5890] Pages: 8

DOI: 10.2174/1381612811319330007

Price: $65

Abstract

It is recognized that the development of atherosclerosis involves many elements of an inflammatory process, involving components of both the innate and adaptive immune systems. The presence and roles of macrophages and T-cells in atherogenesis are wellestablished. More recently dendritic cells have been identified in the vasculature and in atherosclerotic lesions. This review summarises our current understanding of the roles of dendritic cells in the development and regression of atherosclerosis.

Keywords: Dendritic cells, atherosclerosis.


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