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Current Cardiology Reviews

Editor-in-Chief

ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

Embolic Protection Devices in Saphenous Vein Graft and Native Vessel Percutaneous Intervention: A Review

Author(s): Eron Sturm, David Goldberg and Sheldon Goldberg

Volume 8 , Issue 3 , 2012

Page: [192 - 199] Pages: 8

DOI: 10.2174/157340312803217201

Price: $65

Abstract

The clinical benefit of percutaneous intervention (PCI) depends on both angiographic success at the site of intervention as well as the restoration of adequate microvascular perfusion. Saphenous vein graft intervention is commonly associated with evidence of distal plaque embolization, which is correlated with worse clinical outcomes. Despite successful epicardial intervention in the acute MI patient treated with primary PCI, distal tissue perfusion may still be absent in up to 25% of cases [1-3]. Multiple devices and pharmacologic regimens have been developed and refined in an attempt to protect the microvascular circulation during both saphenous vein graft intervention and primary PCI in the acute MI setting. We will review the evidence for various techniques for embolic protection of the distal myocardium during saphenous vein graft PCI and primary PCI in the native vessel.

Keywords: Embolic protection devices, microvascular obstruction, no-reflow, plaque embolization, saphenous vein grafts, thrombus embolization


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