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Current Drug Safety


ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Epidural Steroid Injections Do Not Induce Weight Gain

Author(s): Silviu Brill, Andrei Swartz and Gherta Brill

Volume 2 , Issue 2 , 2007

Page: [113 - 116] Pages: 4

DOI: 10.2174/157488607780598322

Price: $65


Objective: Neuraxial administration of steroids have been used in clinical practice for more than 50 years and have a well defined place in the treatment of radicular low back pain. However, steroids have widespread effects on almost all body systems, such as suppression of the pituitary-adrenal axis with consecutive weight gain and osteoporosis. Methods: We prospectively evaluated the effect of three consecutive epidural steroid injections with 40 mg. methylprednisolone acetate once monthly for 3 months on weight gain. The study population included 108 patients, who attended the pain clinic for chronic low back pain. Completed data were available for 100 patients. Results: We found no significant change in weight after administration of a series of three-epidural steroid injections. Discussion: It appears that neuraxial steroids administration doesnt induce weight gain.

Keywords: Epidural steroid injection, weight gain, low back pain

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