Generic placeholder image

Current Medicinal Chemistry - Central Nervous System Agents

Editor-in-Chief

ISSN (Print): 1568-0150
ISSN (Online): 1875-6158

Ghrelin: A Gastric Peptide that Regulates Hypothalamic Control of Feeding

Author(s): H. Yamaguchi, M. Nakazato and K. Kangawa

Volume 3 , Issue 3 , 2003

Page: [177 - 188] Pages: 12

DOI: 10.2174/1568015033477758

Price: $65

Abstract

Ghrelin, a novel growth-hormone-releasing peptide isolated from human and rat stomach, is a 28-amino acid peptide with a posttranslational acylation modification that is indispensable for its activity. Ghrelin stimulates secretion of growth hormone, food intake, and body weight gain. This review will focus on the discovery, structural characteristics, tissue distribution, and physiological functions of ghrelin, as well as the regulation of its expression and secretion. Future directions of clinical application of ghrelin as an anabolic peptide are discussed.

Keywords: Ghrelin


Rights & Permissions Print Export Cite as
© 2022 Bentham Science Publishers | Privacy Policy