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Medicinal Chemistry Reviews - Online (Discontinued)


ISSN (Print): 1567-2034
ISSN (Online): 1567-2034

Prospects for a Human Toxoplasma Vaccine

Author(s): D. T. Bout, M.- N. Mevelec, I. Dimier-Poisson, M. Lebrun and N. Moire

Volume 2 , Issue 1 , 2005

Page: [65 - 65] Pages: 1

DOI: 10.2174/1567203052996997

Price: $65


Two recent lines of data open the way to development of subunit vaccines. It is now clearly established that ligands of TLR or signalling receptors of DCs could be used as potent adjuvants for vaccination purposes. In addition, it is possible to potentiate DNA vaccines by including cytokine genes.

Keywords: dendritic cells, immune system, toll-like receptors, signalling receptors, toxoplasma gondii, peptidoglycans

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