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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound

Author(s): Chuansheng Shen, Yumin Zhang, Yuanming Gan, Tianqi Zhao and Qiang Gu

Volume 8 , Issue 4 , 2011

Page: [278 - 281] Pages: 4

DOI: 10.2174/157017811795371467

Price: $65


An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5- yl)methanol derivatives has been developed. (3-Phenylisoxazol-5-yl)-methanol derivatives with biological and pharmaceutical property have been synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.

Keywords: Ultrasound, aldoximes, 1,3-dipolar cycloaddition, nitrile oxide, isoxazole, one-pot synthesis, pharmacophores, hydroxylamine, herbicide, phenylisoxazol

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