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Current Drug Delivery

Editor-in-Chief

ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

Particulate Systems as Adjuvants and Carriers for Peptide and Protein Antigens

Author(s): Ming Tao Liang, Nigel M. Davies, Joanne T. Blanchfield and Istvan Toth

Volume 3 , Issue 4 , 2006

Page: [379 - 388] Pages: 10

DOI: 10.2174/156720106778559029

Price: $65

Abstract

The most common feature for antigen-delivery systems is their particulate nature. Together with a certain depot effect, it is the particulate nature that primarily dictates whether the antigen-delivery system will be successful in inducing a certain type and strength of immune response. In this article, we will summarize recent data on particulate delivery systems for peptide and protein antigens with a main focus on lipid or polymer-based particles, all of which possess high potential as both preventive and therapeutic vaccines for parenteral, nasal, and possibly oral administration.

Keywords: Vaccine delivery, particulate delivery system, peptide or protein antigen, lipid, polymer


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