Abstract
Eight peptides were isolated from Bothrops moojeni venom by filtration followed by HPLC. MALDI mass spectroscopy and Edman degradation determined the purity, Mr and sequence of the peptides, respectively. Three (BmP7, BmP8 and BmvP11) of them were homologues with the biologically active B. jararaca bradykinin potentiating peptides while the other with peptides or protein from different sources.
Keywords: Bothrops moojeni, BRADYKININ, algesic hypotensive substance, Kininogenases, angiotensin I to II, angiotensin convertase, antihypertensive drugs, bradykinin potentiating peptides (BPPs)
Protein & Peptide Letters
Title: Bothrops Moojeni Venom Peptides Containing Bradykinin Potentiating Peptides Sequences
Volume: 8 Issue: 1
Author(s): S. C. Bourguignon, F. S. Paes, E. B. Calheiros, M. Juliano, A. S. Aguiar, A. R. Melgarejo and S. Giovanni-De-Simone
Affiliation:
Keywords: Bothrops moojeni, BRADYKININ, algesic hypotensive substance, Kininogenases, angiotensin I to II, angiotensin convertase, antihypertensive drugs, bradykinin potentiating peptides (BPPs)
Abstract: Eight peptides were isolated from Bothrops moojeni venom by filtration followed by HPLC. MALDI mass spectroscopy and Edman degradation determined the purity, Mr and sequence of the peptides, respectively. Three (BmP7, BmP8 and BmvP11) of them were homologues with the biologically active B. jararaca bradykinin potentiating peptides while the other with peptides or protein from different sources.
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Bourguignon C. S., Paes S. F., Calheiros B. E., Juliano M., Aguiar S. A., Melgarejo R. A. and Giovanni-De-Simone S., Bothrops Moojeni Venom Peptides Containing Bradykinin Potentiating Peptides Sequences, Protein & Peptide Letters 2001; 8 (1) . https://dx.doi.org/10.2174/0929866013409689
DOI https://dx.doi.org/10.2174/0929866013409689 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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