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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Recent Studies on Natural Products as Anticancer Agents

Author(s): Angel G. Ravelo, Ana Estevez-Braun, Haydee Chavez-Orellana, Elisa Perez-Sacau and Dulce Mesa-Siverio

Volume 4 , Issue 2 , 2004

Page: [241 - 265] Pages: 25

DOI: 10.2174/1568026043451500

Price: $65

Abstract

Cancer will be the major cause of death in the 21st century and natural products should provide novel and more effective anticancer agents. This review deals with new natural molecules liable to become anticancer drugs, as well as recent specific strategies for a selective treatment of cancer. The introduction presents the current state of the art on anticancer research. Beside, in the following subheadings we summarize our research on cytotoxic natural quinone methide-triperpenes and their analogues. We also discuss our results on the anti-tumour promoting activity of natural naphthoquinones and their derivatives.

Keywords: Anticancer Agents, methide-triperpenes, quinone


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