Prevention of Cell Damage in Ischaemic-Reperfusion: Mitochondrial Respiratory Chain as a Pharmacological Target

Title: Prevention of Cell Damage in Ischaemic-Reperfusion: Mitochondrial Respiratory Chain as a Pharmacological Target

Volume: 1 Issue: 3

Author(s): D. Morin, R. Zini, J. P. Tillement and A. Berdeaux

Affiliation:

Keywords: Ischaemia, reperfusion, mitochondrion, respiratory chain, atp, anti-ischaemic drugs

Abstract: Ischaemic diseases, a major public health problem worldwide, are associated with a decrease in oxygen supply to mitochondria that impairs respiration, energy production and constitute stimuli for cell death. This paper summarises the pharmacological strategies targeting the mitochondrial respiratory chain, which represents an interesting therapeutic perspective.

Cite this article as:

Morin D., Zini R., Tillement P. J. and Berdeaux A., Prevention of Cell Damage in Ischaemic-Reperfusion: Mitochondrial Respiratory Chain as a Pharmacological Target, Letters in Drug Design & Discovery 2004; 1 (3) . https://dx.doi.org/10.2174/1570180043398803