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Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Caveats Regarding the Use of IL-10 and IL-10 Antagonist as Immunotherapeutic Factors

Author(s): Jesus Colino

Volume 4 , Issue 7 , 2007

Page: [487 - 495] Pages: 9

DOI: 10.2174/157018007781788552

Price: $65


IL-10 is an anti-inflammatory cytokine widely regarded as an inhibitor of immunity. Thus IL-10 and IL-10 antagonist have been proposed as promising therapeutic factors for the treatment of inflammatory diseases and pathogen infections. Here the potential risk of favoring secondary pathogen infections with these therapies is underscored.

Keywords: IL-10, IL-10 antagonists, Immunotherapy

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