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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Intraperitoneal Chemotherapy as First-Line Treatment in the Management of Epithelial Ovarian Cancer

Author(s): S. Rekhraj, J. Kinross, S. Prabhudesai, A. Darzi and P. Ziprin

Volume 7 , Issue 5 , 2007

Page: [511 - 519] Pages: 9

DOI: 10.2174/138955707780619644

Price: $65

Abstract

Recent evidence has suggested improved outcomes following incorporation of intraperitoneal chemotherapy administration with intravenous systemic chemotherapy as first-line treatment of small volume residual epithelial ovarian cancer. This review focuses on the mechanism of actions of the chemotherapeutic drugs and reviews the possible reasons for the superior outcomes of intraperitoneal chemotherapy.

Keywords: Intraperitoneal chemotherapy, cisplatin, carboplatin, paclitaxel, ovarian cancer management


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