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Current Alzheimer Research


ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

A Commentary on Neuronal Degeneration and Cell Death in Guam ALS and PD: An Evolutionary Process of Understanding

Author(s): Ralph M. Garruto

Volume 3 , Issue 4 , 2006

Page: [397 - 401] Pages: 5

DOI: 10.2174/156720506778249425


The Twentieth Century witnessed tremendous advances in our understanding of neurodegenerative diseases. Not least among them were the contributions from hyperendemic foci of neurodegenerative disorders in isolated human groups worldwide, with the knowledge gained applicable to our understanding of related neurodegenerative diseases globally.

Keywords: Gene-environment interaction, mitochondrial dysfunction, genetic susceptibility

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