Advances in Umbilical Cord Blood Transplantation

Karen   K.   Ballen

doi:10.2174/157488806778226858

Abstract

The first successful cord blood transplant was reported in 1989. In the last sixteen years, there has been a substantial increase in the use of cord blood as an alternative stem cell source for patients without matched related or unrelated bone marrow donors. Approximately 5000 cord blood transplants have been performed worldwide. Recently, the results in adult cord blood transplantation appear promising. In this review, the preclinical background, cord blood banking, and ethical issues will be briefly addressed. Outcome data for both pediatric and adult transplantation will be reviewed, with an emphasis on new strategies for adult cord blood transplantation. New indications for cord blood use outside of hematology/oncology will also be explored.

Keywords: Umbilical cord blood, transplantation

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Current Stem Cell Research & Therapy

Title: Advances in Umbilical Cord Blood Transplantation

Volume: 1 Issue: 3

Author(s): Karen K. Ballen

Affiliation:

Keywords: Umbilical cord blood, transplantation

Abstract: The first successful cord blood transplant was reported in 1989. In the last sixteen years, there has been a substantial increase in the use of cord blood as an alternative stem cell source for patients without matched related or unrelated bone marrow donors. Approximately 5000 cord blood transplants have been performed worldwide. Recently, the results in adult cord blood transplantation appear promising. In this review, the preclinical background, cord blood banking, and ethical issues will be briefly addressed. Outcome data for both pediatric and adult transplantation will be reviewed, with an emphasis on new strategies for adult cord blood transplantation. New indications for cord blood use outside of hematology/oncology will also be explored.

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Cite this article as:

Ballen K. Karen, Advances in Umbilical Cord Blood Transplantation, Current Stem Cell Research & Therapy 2006; 1 (3) . https://dx.doi.org/10.2174/157488806778226858

DOI https://dx.doi.org/10.2174/157488806778226858	Print ISSN 1574-888X
Publisher Name Bentham Science Publisher	Online ISSN 2212-3946

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