Generic placeholder image

Current Psychiatry Research and Reviews

Editor-in-Chief

ISSN (Print): 2666-0822
ISSN (Online): 2666-0830

Review Article (Mini-Review)

Disruptive Mood Dysregulation Disorder and its Impact on Rates of Bipolar Disorder among Children and Adolescents

Author(s): Waleed A. Alghamdi*

Volume 16 , Issue 3 , 2020

Page: [154 - 157] Pages: 4

DOI: 10.2174/2666082216999200909113835

Price: $65

Abstract

Background: In 2013, Disruptive Mood Dysregulation Disorder (DMDD) was introduced in the DSM-5 in part to curb the rapid rise in the rates of bipolar diagnosis among children and adolescents during the decade before the DSM-5 publication. DMDD proved to be a controversial diagnosis for many reasons.

Objective: This brief review aims to provide an overview of the DMDD diagnosis and its origins and summarize available data on the impact of the introduction of the DMDD diagnosis on the rates of bipolar disorder among children and adolescents.

Methods: Multiple scientific databases were searched using the related terms “DMDD”, “Disruptive Mood Dysregulation”, and “pediatric bipolar disorder” in combination with the terms “diagnosis” and “impact”. The retrieved articles were reviewed carefully.

Results: The DMDD diagnosis rates have steadily increased since its introduction. Furthermore, available data show a decrease in the rates of bipolar disorder diagnosis among children and adolescents over the past few years.

Conclusion: The very limited available data since 2013 show a decline in the diagnosis of bipolar disorder among children and adolescents. More time and further research are needed to more accurately determine the impact of the DMDD diagnosis on the rates of bipolar disorder in this population.

Keywords: Disruptive mood dysregulation, bipolar disorder, irritability, diagnosis, impact, pediatric.

Graphical Abstract
[1]
American Psychiatric Association Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association Publishing 2013.
[2]
Axelson D, Findling RL, Fristad MA, et al. Examining the proposed disruptive mood dysregulation disorder diagnosis in children in the Longitudinal Assessment of Manic Symptoms study. J Clin Psychiatry 2012; 73(10): 1342-50.
[http://dx.doi.org/10.4088/JCP.12m07674 ] [PMID: 23140653]
[3]
Moreno C, Laje G, Blanco C, Jiang H, Schmidt AB, Olfson M. National trends in the outpatient diagnosis and treatment of bipolar disorder in youth. Arch Gen Psychiatry 2007; 64(9): 1032-9.
[http://dx.doi.org/10.1001/archpsyc.64.9.1032 ] [PMID: 17768268]
[4]
Blader JC, Carlson GA. Increased rates of bipolar disorder diagnoses among U.S. child, adolescent, and adult inpatients, 1996-2004. Biol Psychiatry 2007; 62(2): 107-14.
[http://dx.doi.org/10.1016/j.biopsych.2006.11.006 ] [PMID: 17306773]
[5]
Roy AK, Lopes V, Klein RG. Disruptive mood dysregulation disorder: a new diagnostic approach to chronic irritability in youth. Am J Psychiatry 2014; 171(9): 918-24.
[http://dx.doi.org/10.1176/appi.ajp.2014.13101301 ] [PMID: 25178749]
[6]
Rao P, Moore J, Stewart R, et al. Bipolar disorder in children and adolescents: diagnostic inpatient rates from 2000 to 2013 in Germany. Int J Bipolar Disord 2016; 4: 23.
[http://dx.doi.org/10.1186/s40345-016-0064-2]
[7]
Kessing LV, Vradi E, Andersen PK. Are rates of pediatric bipolar disorder increasing? Results from a nationwide register study. Int J Bipolar Disord 2014; 2(1): 10.
[http://dx.doi.org/10.1186/s40345-014-0010-0 ] [PMID: 25243107]
[8]
Parker G, Tavella G. Disruptive mood dysregulation disorder: a critical perspective. Can J Psychiatry 2018; 63(12): 813-5.
[http://dx.doi.org/10.1177/0706743718789900 ] [PMID: 30009630]
[9]
Leibenluft E, Charney DS, Towbin KE, Bhangoo RK, Pine DS. Defining clinical phenotypes of juvenile mania. Am J Psychiatry 2003; 160(3): 430-7.
[http://dx.doi.org/10.1176/appi.ajp.160.3.430 ] [PMID: 12611821]
[10]
Leibenluft E. Severe mood dysregulation, irritability, and the diagnostic boundaries of bipolar disorder in youths. Am J Psychiatry 2011; 168: 129-42.
[http://dx.doi.org/10.1176/appi.ajp.2010.10050766]
[11]
Copeland WE, Angold A, Costello EJ, Egger H. Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder. Am J Psychiatry 2013; 170(2): 173-9.
[http://dx.doi.org/10.1176/appi.ajp.2012.12010132 ] [PMID: 23377638]
[12]
Margulies DM, Weintraub S, Basile J, Grover PJ, Carlson GA. Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children? Bipolar Disord 2012; 14(5): 488-96.
[http://dx.doi.org/10.1111/j.1399-5618.2012.01029.x ] [PMID: 22713098]
[13]
Faheem S, Petti V, Mellos G. Disruptive mood dysregulation disorder and its effect on bipolar disorder. Ann Clin Psychiatry 2017; 29(1): 84-91.
[PMID: 28207918]
[14]
Le J, Feygin Y, Creel L, et al. Trends in diagnosis of bipolar and disruptive mood dysregulation disorders in children and youth. J Affect Disord 2020; 264: 242-8.
[http://dx.doi.org/10.1016/j.jad.2019.12.018 ] [PMID: 32056757]

Rights & Permissions Print Export Cite as
© 2022 Bentham Science Publishers | Privacy Policy