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Current Diabetes Reviews


ISSN (Print): 1573-3998
ISSN (Online): 1875-6417

Systematic Review Article

Mindfulness Practice for Glycemic Control: Could it be a New Strategy for an Old Problem? A Systematic Review and Meta-Analysis

Author(s): Ângela Cristine Bersch-Ferreira, Bernardete Weber, João Gabriel Sanchez Tavares da Silva, Raira Pagano, Mabel Fernandes Figueiro, Lucas Ribeiro da Silva, Luís Gustavo de Souza Mota, Erica Aranha Suzumura, Camila Ragne Torreglosa, Enilda de Sousa Lara, Driele Quinhoneiro, Edilaine Cristina da Silva Gherardi-Donato, Priscila Regina Torres Bueno and Aline Marcadenti*

Volume 17 , Issue 7 , 2021

Published on: 10 August, 2020

Article ID: e081020184730 Pages: 16

DOI: 10.2174/1573399816666200810131055

Price: $65


Background: The management of type 2 diabetes mellitus (T2DM) requires a complex and organized care that includes patient’s lifestyle change. Additionally, emotional well-being is an important part of self-management, and it may impair the individual’s adherence. Therefore, equipping the patients with the necessary coping and self-care techniques may be an important step in managing diabetes.

Objective: To evaluate the effect of interventions using established mindfulness-based protocols on glycemic control of individuals with T2DM.

Methods: Data sources: Two electronic databases (PubMed and EMBASE) were searched from inception to December 2019. We limited our search to published studies in English, Spanish and Portuguese languages.

Study Selection: Randomized clinical trials that assessed the effects of mindfulness in individuals with T2DM were selected.

Data Extraction: Two authors independently assessed the risk of bias and extracted data from the included trials. Data were pooled using inverse-variance random-effects meta-analyses. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.

Results: Four randomized trials were included. There were no differences in blood glucose change (mean difference between groups (MD) -0.73mg/dl; 95% CI, -10.49; 9.02; I2 =0%; very low quality of evidence) or glycated hemoglobin (MD 0.05%; 95%CI -0.22 to 0.32; I2 =29%; very low quality of evidence).

Conclusion: Although the quality of current evidence is very low, our findings suggest that established protocols involving mindfulness have no effect on blood glucose or glycated hemoglobin in individuals with T2DM. Indeed, large-scale trials are needed to evaluate the contribution of mindfulness to glycemic control in clinical practice. PROSPERO Registration ID: RD42020161940.

Keywords: Mindfulness, diabetes mellitus, type 2, glycated hemoglobin, blood glucose, systematic review, meta-analysis.

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