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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Review Article

Flavonoids and other Non-alkaloidal Constituents of Genus Erythrina: Phytochemical Review

Author(s): Ninh T. Son* and Abdelsamed I. Elshamy

Volume 24 , Issue 1 , 2021

Published on: 09 June, 2020

Page: [20 - 58] Pages: 39

DOI: 10.2174/1386207323666200609141517

Price: $65

Abstract

Background: Genus Erythrina belongs to family Fabaceae, which is widely distributed in tropical and subtropical areas. It has been used in both traditional herbal medicines and pharmacological applications. Original research articles and publications on the overview of alkaloids related to this genus are available, but a supportive systematic review account which highlighted phytochemical aspects of other types of secondary metabolites is currently insufficient.

Objective: With the utilization of data and information from SCI-Finder, Google Scholar, the Web of Science, Scopus, Science Direct, PubMed, Chemical Abstracts, ACS journals, Springer, Taylor Francis, Bentham Science and IOP Science, the reliable material sources of this systematic review paper were obtained from the literature published from the 1980s to now.

Conclusion: A vast amount of data showed that the non-alkaloidal secondary metabolites were obtained from genus Erythrina with various classes of chemical structures. Herein, approximately five hundred constituents were isolated, comprising flavonoids, terpenoids, saponins, phytosterols, phenols, arylbenzofurans, coumarins, alcohols, ceramides, mono-sugars and fatty acid derivatives. In agreement with the previous phytochemical reports on the plants of the family Fabaceae, flavonoids reached a high amount in the plants of genus Erythrina. Numerous biological activity investigations such as anti-bacteria, anti-cancer, anti-virus using isolated compounds from Erythrina species suggested that secondary metabolites of Erythrina plants are now becoming the promising agents for drug developments.

Keywords: Genus Erythrina, non-alkaloidal, secondary metabolites, phytochemistry, isolation, phytosterols, arylbenzofurans.

[1]
Shukla, S.; Mehta, A.; Mehta, P.; Vyas, S.P.; Shukla, S.; Bajpai, V.K. Studies on anti-inflammatory, antipyretic and analgesic properties of Caesalpinia bonducella F. seed oil in experimental animal models. Food Chem. Toxicol., 2010, 48(1), 61-64.
[http://dx.doi.org/10.1016/j.fct.2009.09.015] [PMID: 19766160]
[2]
Vieira, D.R.; Amaral, F.M.; Maciel, M.C.; Nascimento, F.R.; Libério, S.A.; Rodrigues, V.P. Plant species used in dental diseases: ethnopharmacology aspects and antimicrobial activity evaluation. J. Ethnopharmacol., 2014, 155(3), 1441-1449.
[http://dx.doi.org/10.1016/j.jep.2014.07.021] [PMID: 25046828]
[3]
Lahlou, M. Screening of natural products for drug discovery. Expert Opin. Drug Discov., 2007, 2(5), 697-705.
[http://dx.doi.org/10.1517/17460441.2.5.697] [PMID: 23488959]
[4]
Kumar, A.; Lingadurai, S.; Jain, A.; Barman, N.R. Erythrina variegata Linn: A review on morphology, phytochemistry, and pharmacological aspects. Pharmacogn. Rev., 2010, 4(8), 147-152.
[http://dx.doi.org/10.4103/0973-7847.70908] [PMID: 22228954]
[5]
Gessler, M.C.; Nkunya, M.H.; Mwasumbi, L.B.; Heinrich, M.; Tanner, M. Screening Tanzanian medicinal plants for antimalarial activity. Acta Trop., 1994, 56(1), 65-77.
[http://dx.doi.org/10.1016/0001-706X(94)90041-8] [PMID: 8203297]
[6]
Fomum, Z.T.; Ayafor, J.F. Erythrina studies. Part 2. Structures of three novel prenylated antibacterial flavaones, sigmodins A-C, from Erythrina singmoidea Hua. J. Chem. Soc. Perkin Trans, 1986, 1, 33-37.
[http://dx.doi.org/10.1039/P19860000033]
[7]
de Oliveira, D.R.; Zamberlam, C.R.; Gaiardo, R.B.; Rêgo, G.M.; Cerutti, J.M.; Cavalheiro, A.J.; Cerutti, S.M. Flavones from Erythrina falcata are modulators of fear memory. BMC Complement. Altern. Med., 2014, 14, 288.
[http://dx.doi.org/10.1186/1472-6882-14-288] [PMID: 25096710]
[8]
Togola, A.; Hedding, B.; Theis, A.; Wangensteen, H.; Rise, F.; Smestad Paulsen, B.; Diallo, D.; Egil Malterud, K. 15-Lipoxygenase inhibitory effects of prenylated flavonoids from Erythrina senegalensis. Planta Med., 2009, 75(10), 1168-1170.
[http://dx.doi.org/10.1055/s-0029-1185449] [PMID: 19288405]
[9]
Njamen, D.; Talla, E.; Mbafor, J.T.; Fomum, Z.T.; Kamanyi, A.; Mbanya, J.C.; Cerdá-Nicolás, M.; Giner, R.M.; Recio, M.C.; Ríos, J.L. Anti-inflammatory activity of erycristagallin, a pterocarpene from Erythrina mildbraedii. Eur. J. Pharmacol., 2003, 468(1), 67-74.
[http://dx.doi.org/10.1016/S0014-2999(03)01664-9] [PMID: 12729844]
[10]
Bedane, K.G.; Kusari, S.; Masesane, I.B.; Spiteller, M.; Majinda, R.R. Flavanones of Erythrina livingstoniana with antioxidant properties. Fitoterapia, 2016, 108, 48-54.
[http://dx.doi.org/10.1016/j.fitote.2015.11.014] [PMID: 26592853]
[11]
Ghosal, S.; Dutta, S.K.; Bhattacharya, S.K. Erythrina--chemical and pharmacological evaluation II: Alkaloids of Erythrina variegata L. J. Pharm. Sci., 1972, 61(8), 1274-1277.
[http://dx.doi.org/10.1002/jps.2600610821] [PMID: 5050377]
[12]
Passreiter, C.M.; Suckow-Schnitker, A.K.; Kulawik, A.; Addae-Kyereme, J.; Wright, C.W.; Wätjen, W. Prenylated flavanone derivatives isolated from Erythrina addisoniae are potent inducers of apoptotic cell death. Phytochemistry, 2015, 117, 237-244.
[http://dx.doi.org/10.1016/j.phytochem.2015.04.002] [PMID: 26101145]
[13]
Cui, L.; Ndinteh, D.T.; Na, M.; Thuong, P.T.; Silike-Muruumu, J.; Njamen, D.; Mbafor, J.T.; Fomum, Z.T.; Ahn, J.S.; Oh, W.K. Isoprenylated flavonoids from the stem bark of Erythrina abyssinica. J. Nat. Prod., 2007, 70(6), 1039-1042.
[http://dx.doi.org/10.1021/np060477+] [PMID: 17489632]
[14]
Tanaka, H.; Oh-Uchi, T.; Etoh, H.; Sako, M.; Asai, F.; Fukai, T.; Sato, M.; Murata, J.; Tateishi, Y. Isoflavonoids from roots of Erythrina zeyheri. Phytochemistry, 2003, 64(3), 753-758.
[http://dx.doi.org/10.1016/S0031-9422(03)00390-X] [PMID: 13679098]
[15]
Rukachaisirikul, T.; Innok, P.; Suksamrarn, A. Erythrina alkaloids and a pterocarpan from the bark of Erythrina subumbrans. J. Nat. Prod., 2008, 71(1), 156-158.
[http://dx.doi.org/10.1021/np070506w] [PMID: 18171023]
[16]
Cui, L.; Thuong, P.T.; Lee, H.S.; Njamen, D.; Mbafor, J.T.; Fomum, Z.T.; Lee, J.; Kim, Y.H.; Oh, W.K. Four new chalcones from Erythrina abyssinica. Planta Med., 2008, 74(4), 422-426.
[http://dx.doi.org/10.1055/s-2008-1034327] [PMID: 18484536]
[17]
Miguel-Chavez, R.S.; Soto-Hernandez, M.; Ramos-Valdivia, A.C.; Kite, G. Alkaloid production in elicited cell suspension cultures of Erythrina americana Miller. Phytochem. Rev., 2007, 6, 167-173.
[http://dx.doi.org/10.1007/s11101-006-9045-x]
[18]
Raven, P.H. Erythrina (Fabaceae): Achievements and opportunities. Lloydia, 1974, 37, 321-331.
[19]
Singh, H.; Chawla, A.S.; Kapoor, V.K.; Kumar, N. Investigation of Erythrina spp. IX. Chemical constituents of Erythrina stricta bark. J. Nat. Prod., 1981, 44, 526-529.
[http://dx.doi.org/10.1021/np50017a002]
[20]
Kamat, V.S.; Chuo, F.Y.; Kubo, I.; Nakanishi, K. Antimicrobial agents from an East African medicinal plant Erythrina abyssinica. Heterocycles, 1981, 15, 1163-1170.
[http://dx.doi.org/10.3987/S-1981-02-1163]
[21]
Ali, M.S.; Ali, M.I.; Onocha, P.A.; Ahmed, Z. bis-Sigmodiol: a new prenylflavanone dimer from Erythrina sigmoidea Hua (Fabaceae) of Nigeria. J. Asian Nat. Prod. Res., 2011, 13(2), 182-187.
[http://dx.doi.org/10.1080/10286020.2010.546352] [PMID: 21279883]
[22]
Bedane, K.G.; Kusari, S.; Bullach, A.; Masesane, I.B.; Mihigo, S.O.; Spiteller, M.; Majida, R.R.T. Chemical constituents of the root bark of Erythrina droogmansiana. Phytochem. Lett., 2017, 20, 84-88.
[http://dx.doi.org/10.1016/j.phytol.2017.04.005]
[23]
Dagne, E.; Gunatilaka, A.A.; Kingston, D.G.; Alemu, M.; Hofmann, G.; Johnson, R.K. Two bioactive pterocarpans from Erythrina burana. J. Nat. Prod., 1993, 56(10), 1831-1834.
[http://dx.doi.org/10.1021/np50100a028] [PMID: 8277323]
[24]
Dao, T.T.; Nguyen, P.H.; Thuong, P.T.; Kang, K.W.; Na, M.; Ndinteh, D.T.; Mbafor, J.T.; Oh, W.K. Pterocarpans with inhibitory effects on protein tyrosine phosphatase 1B from Erythrina lysistemon Hutch. Phytochemistry, 2009, 70(17-18), 2053-2057.
[http://dx.doi.org/10.1016/j.phytochem.2009.09.012] [PMID: 19833362]
[25]
Djiogue, S.; Halabalaki, M.; Alexi, X.; Njamen, D.; Fomum, Z.T.; Alexis, M.N.; Skaltsounis, A.L. Isoflavonoids from Erythrina poeppigiana: Evaluation of their binding affinity for the estrogen receptor. J. Nat. Prod., 2009, 72(9), 1603-1607.
[http://dx.doi.org/10.1021/np900271m] [PMID: 19705860]
[26]
Emmanuel, T.; Joel, Y.G.; Laurel, M.K.; Pierre, A.J.; Alembert, T.; Frederich, M.; Joseph, M.T. Chemical constituents from Erythrina droogmansiana (Fabaceae), radical scavenging and antibacterial potential of some extracts and compounds. NPAIJ, 2016, 12, 12-20.
[27]
Fomum, Z.T.; Ayafor, J.; Wandji, J.; Fomban, W.G.; Nkengfack, A.E. Erythrinasinate, an ester from three Erythrina species. Phytochemistry, 1986, 25, 757-759.
[http://dx.doi.org/10.1016/0031-9422(86)88044-X]
[28]
Gurmessa, G.T.; Kusari, S.; Laatsch, H.; Bojase, G.; Tatolo, G.; Masesane, I.B.; Spiteller, M.T.; Majinda, R. Chemical constituents of root and stem bark of Erythrina brucei. Phytochem. Lett., 2018, 25, 37-42.
[http://dx.doi.org/10.1016/j.phytol.2018.03.006]
[29]
Hegde, V.R.; Dai, P.; Patel, M.G.; Puar, M.S.; Das, P.; Pai, J.; Bryant, R.; Cox, P.A. Phospholipase A2 inhibitors from an Erythrina species from Samoa. J. Nat. Prod., 1997, 60, 537-539.
[http://dx.doi.org/10.1021/np960533e]
[30]
Innok, P.; Rukachaisirikul, T.; Suksamrarn, A. Flavanoids and pterocarpans from the bark of Erythrina fusca. Chem. Pharm. Bull. (Tokyo), 2009, 57(9), 993-996.
[http://dx.doi.org/10.1248/cpb.57.993] [PMID: 19721263]
[31]
Innok, P.; Rukachaisirikul, T.; Phongpaichit, S.; Suksamrarn, A. Fuscacarpans A-C, new pterocarpans from the stems of Erythrina fusca. Fitoterapia, 2010, 81(6), 518-523.
[http://dx.doi.org/10.1016/j.fitote.2010.01.009] [PMID: 20079815]
[32]
Kuete, V.; Sandjo, L.P.; Djeussi, D.E.; Zeino, M.; Kwamou, G.M.; Ngadjui, B.; Efferth, T. Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells. Invest. New Drugs, 2014, 32(6), 1053-1062.
[http://dx.doi.org/10.1007/s10637-014-0137-y] [PMID: 25034000]
[33]
Kuete, V.; Sandjo, L.P.; Kwamou, G.M.; Wiench, B.; Nkengfack, A.E.; Efferth, T. Activity of three cytotoxic isoflavonoids from Erythrina excelsa and Erythrina senegalensis (neobavaisoflavone, sigmoidin H and isoneorautenol) toward multi-factorial drug resistant cancer cells. Phytomedicine, 2014, 21(5), 682-688.
[http://dx.doi.org/10.1016/j.phymed.2013.10.017] [PMID: 24252341]
[34]
Kwamou, G.M.; Sandjo, L.P.; Kuete, V.; Wandja, A.A.K.; Tankeo, S.B.; Efferth, T.; Nkengfack, A.E. Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity. Nat. Prod. Res., 2015, 29(10), 921-925.
[http://dx.doi.org/10.1080/14786419.2014.959519] [PMID: 25220189]
[35]
Machumi, F.; Bojase-Moleta, G.; Mapitse, R.; Masesane, I.; Majinda, R. Radical scavenging-flavonoids from Erythrina abyssinica. Nat. prod. Comm., 2006, 1, 287-292.
[36]
El-Masry, S.; Hammoda, H.; Zaatout, H.; Alqasoumi, S.; Abdel-Kader, M. Constituents of Erythrina caffra stem bark grown in Egypt. Nat. Prod. Sci., 2010, 16, 211-216.
[37]
McKee, T.C.; Bokesch, H.R.; McCormick, J.L.; Rashid, M.A.; Spielvogel, D.; Gustafson, K.R.; Alavanja, M.M.; Cardelline, J.H., II; Boyd, M.R. Isolation and characterization of new anti-HIV and cytotoxic leads from plants, marine, and microbial organisms. J. Nat. Prod., 1997, 60(5), 431-438.
[http://dx.doi.org/10.1021/np970031g] [PMID: 9170286]
[38]
Mitscher, L.; Okwute, S.; Gollapudi, S.; Drake, S.; Avona, E. Antimicrobial pterocarpans of nigerian Erythrina mildbraedii. Phytochemistry, 1988, 27, 3449-3452.
[http://dx.doi.org/10.1016/0031-9422(88)80746-5]
[39]
Mitscher, L.A.; Gollapudi, S.R.; Gerlach, D.C.; Drake, S.D.; Vehz, E.A.; Ward, J.A. Erycristin, a new antimicrobial petrocarpan from Erythrina crista-galli. Phytochemistry, 1988, 27, 381-385.
[http://dx.doi.org/10.1016/0031-9422(88)83103-0]
[40]
Mitsher, L.A.; Okwute, S.K.; Gollapudi, S.R.; Shokri, A.L. Antimicrobial agents from higher plants. The isolation and structural characterization of two additional pterocarpan antimicrobial agents from Nigerian Erythrina mildbraedii. Heterocycles, 1988, 27, 2517-2522.
[http://dx.doi.org/10.3987/COM-88-4624]
[41]
Nguyen, P.H.; Nguyen, T.N.; Dao, T.T.; Kang, H.W.; Ndinteh, D.T.; Mbafor, J.T.; Oh, W.K. AMP-activated protein kinase (AMPK) activation by benzofurans and coumestans isolated from Erythrina abyssinica. J. Nat. Prod., 2010, 73(4), 598-602.
[http://dx.doi.org/10.1021/np900745g] [PMID: 20337486]
[42]
Nguyen, P.H.; Nguyen, T.N.; Kang, K.W.; Ndinteh, D.T.; Mbafor, J.T.; Kim, Y.R.; Oh, W.K. Prenylated pterocarpans as bacterial neuraminidase inhibitors. Bioorg. Med. Chem., 2010, 18(9), 3335-3344.
[http://dx.doi.org/10.1016/j.bmc.2010.03.005] [PMID: 20363636]
[43]
Nguyen, P.H.; Le, T.V.; Thuong, P.T.; Dao, T.T.; Ndinteh, D.T.; Mbafor, J.T.; Kang, K.W.; Oh, W.K. Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica. Bioorg. Med. Chem. Lett., 2009, 19(23), 6745-6749.
[http://dx.doi.org/10.1016/j.bmcl.2009.09.108] [PMID: 19836230]
[44]
Nkengfack, A.E.; Vouffo, T.W.; Vardamidesn, J.C.; Kouam, J.; Fomum, Z.T.; Meyer, M.; Sterner, O. Phenolic metabolites from Erythrina species. Phytochemistry, 1997, 46, 573-578.
[http://dx.doi.org/10.1016/S0031-9422(97)00291-4]
[45]
Nkengfack, A.E.; Vouffo, T.W.; Fomum, Z.T.; Meyer, M.; Bergendorff, O.; Sterner, O. Prenylated isoflavanone from the roots of Erythrina sigmoidea. Phytochemistry, 1994, 36(4), 1047-1051.
[http://dx.doi.org/10.1016/S0031-9422(00)90489-8] [PMID: 7765206]
[46]
Nkengfack, A.E.; Kouam, J.; Vouffo, T.W.; Meyer, M.; Tempesta, M.S.; Fomum, Z.T. An isoflavanone and a coumestan from Erythrina sigmoidea. Phytochemistry, 1994, 35, 521-526.
[http://dx.doi.org/10.1016/S0031-9422(00)94794-0]
[47]
Nkengfack, A.E.; Vouffo, T.W.; Vardamides, J.C.; Fomum, Z.T.; Bergendorff, O.; Sterner, O. Sigmoidins J and K, two new prenylated isoflavonoids from erythrina sigmoidea. J. Nat. Prod., 1994, 57(8), 1172-1177.
[http://dx.doi.org/10.1021/np50110a008] [PMID: 7964799]
[48]
Nkengfack, A.E.; Vardamides, J.C.; Fomum, Z.T.; Meyer, M. Prenylated isoflavanone from Erythrina eriotricha. Phytochemistry, 1995, 40(6), 1803-1808.
[http://dx.doi.org/10.1016/0031-9422(95)00037-8] [PMID: 8590641]
[49]
Nyandoro, S.S.; Munissi, J.J.; Kombo, M.; Mgina, C.A.; Pan, F.; Gruhonjic, A.; Fitzpatrick, P.; Lu, Y.; Wang, B.; Rissanen, K.; Erdélyi, M. Flavonoids from Erythrina schliebenii. J. Nat. Prod., 2017, 80(2), 377-383.
[http://dx.doi.org/10.1021/acs.jnatprod.6b00839] [PMID: 28112509]
[50]
Rabelo, L.A.; de Fátima Agra, M.; da-Cunha, E.V.; da Silva, M.S.; Maria Barbosa-Filho, J. Homohesperetin and phaseollidin from Erythrina velutina. Biochem. Syst. Ecol., 2001, 29(5), 543-544.
[http://dx.doi.org/10.1016/S0305-1978(00)00077-6] [PMID: 11274777]
[51]
Redko, F.; Clavin, M.L.; Weber, D.; Ranea, F.; Anke, T.; Martino, V. Antimicrobial isoflavonoids from Erythrina crista galli infected with Phomopsis sp. Z. Natforsch. C J. Biosci., 2007, 62(3-4), 164-168.
[http://dx.doi.org/10.1515/znc-2007-3-402] [PMID: 17542479]
[52]
Rukachaisirikul, T.; Innok, P.; Aroonrerk, N.; Boonamnuaylap, W.; Limrangsun, S.; Boonyon, C.; Woonjina, U.; Suksamrarn, A. Antibacterial pterocarpans from Erythrina subumbrans. J. Ethnopharmacol., 2007, 110(1), 171-175.
[http://dx.doi.org/10.1016/j.jep.2006.09.022] [PMID: 17055201]
[53]
Rukachaisirikul, T.; Saekee, A.; Tharibun, C.; Watkuolham, S.; Suksamrarn, A. Biological activities of the chemical constituents of Erythrina stricta and Erythrina subumbrans. Arch. Pharm. Res., 2007, 30(11), 1398-1403.
[http://dx.doi.org/10.1007/BF02977363] [PMID: 18087807]
[54]
Rukachaisirikul, T.; Chokchaisiri, S.; Suksamrarn, A. Chemical constituents of the roots of Erythrina subumbrans. Chem. Nat. Compd., 2014, 49, 1127-1128.
[http://dx.doi.org/10.1007/s10600-014-0838-7]
[55]
Sato, M.; Tanaka, H.; Fujiwara, S.; Hirata, M.; Yamaguchi, R.; Etoh, H.; Tokuda, C. Antibacterial property of isoflavonoids isolated from Erythrina variegata against cariogenic oral bacteria. Phytomedicine, 2003, 10(5), 427-433.
[http://dx.doi.org/10.1078/0944-7113-00225] [PMID: 12834009]
[56]
Sato, M.; Tanaka, H.; Oh-Uchi, T.; Fukai, T.; Etoh, H.; Yamaguchi, R. Antibacterial activity of phytochemicals isolated from Erythrina zeyheri against vancomycin-resistant enterococci and their combinations with vancomycin. Phytother. Res., 2004, 18(11), 906-910.
[http://dx.doi.org/10.1002/ptr.1556] [PMID: 15597305]
[57]
Talla, E.; Yankep, E.; Mbafor, J. Chemical constituents from root barks of Erythrina mildbraedii and stem barks of Erythrina addisoniae. Bull. Chem. Soc. Ethiop., 2014, 28, 155-159.
[http://dx.doi.org/10.4314/bcse.v28i1.19]
[58]
Tanaka, H.; Tanaka, T.; Etoh, H. A pterocarpan from Erythrina orientalis. Phytochemistry, 1996, 42, 1173-1475.
[http://dx.doi.org/10.1016/0031-9422(96)00138-0]
[59]
Tanaka, H.; Tanaka, T.; Etoh, H. Three pterocarpans from Erythrina crista-galli. Phytochemistry, 1997, 45, 835-838.
[http://dx.doi.org/10.1016/S0031-9422(97)00071-X]
[60]
Tanaka, H.; Tanaka, T.; Etoh, H. A pterocarpan from Erythrina orientalis. Phytochemistry, 1997, 45, 205-207.
[http://dx.doi.org/10.1016/S0031-9422(96)00841-2]
[61]
Tanaka, H.; Tanaka, T.; Hosoya, A.; Kitade, Y.; Etoh, H. An isoflavan from Erythrina x bidwilli. Phytochemistry, 1998, 47, 1347-1400.
[http://dx.doi.org/10.1016/S0031-9422(97)00732-2]
[62]
Tanaka, H.; Tanaka, T.; Etoh, H. Two pterocarpans from Erythrina orientalis. Phytochemistry, 1998, 47, 475-477.
[http://dx.doi.org/10.1016/S0031-9422(97)00596-7]
[63]
Tanaka, H.; Tanaka, T.; Etoh, H.; Watanabe, N.; Ahmad, M.; Qurashi, I.; Khand, M. Two new isoflavones from Erythrina suberosa var glabrescences. Heterocycles, 1998, 48, 2661-2667.
[http://dx.doi.org/10.3987/COM-98-8334]
[64]
Tanaka, H.; Etoh, H.; Shimizu, H.; Makita, T.; Tateishi, Y. Two new isoflavonoids from Erythrina variegata. Planta Med., 2000, 66(6), 578-579.
[http://dx.doi.org/10.1055/s-2000-8602] [PMID: 10985092]
[65]
Tanaka, H.; Etoh, H.; Watanabe, N.; Shimizu, H.; Ahmad, M.; Rizwani, G.H. Erysubins C-F, four isoflavonoids from Erythrina suberosa var. glabrescences. Phytochemistry, 2001, 56(7), 769-773.
[http://dx.doi.org/10.1016/S0031-9422(00)00441-6] [PMID: 11314966]
[66]
Tanaka, H.; Doi, M.; Etoh, H.; Watanabe, N.; Shimizu, H.; Hirata, M.; Ahmad, M.; Qurashi, I.; Khan, M.R. Revised structures for senegalensin and euchrenone b(10). J. Nat. Prod., 2001, 64(10), 1336-1340.
[http://dx.doi.org/10.1021/np0101696] [PMID: 11678662]
[67]
Tanaka, H.; Hirata, M.; Etoh, H.; Watanabe, N.; Shimizu, H.; Ahmad, M.; Khan, Z.; Anwar, M. Three new isoflavonoids from Erythrina variegate. Heterocycles, 2001, 55, 2341-2347.
[http://dx.doi.org/10.3987/COM-01-9346]
[68]
Tanaka, H.; Oh-Uchi, T.; Etoh, H.; Shimizu, H.; Tateishi, Y. Isoflavonoids from the roots of erythrina poeppigiana. Phytochemistry, 2002, 60(8), 789-794.
[http://dx.doi.org/10.1016/S0031-9422(02)00164-4] [PMID: 12150800]
[69]
Tanaka, H.; Hirata, M.; Etoh, H.; Shimizu, H.; Sako, M.; Murata, J.; Murata, H.; Darnaedi, D.; Fukai, T. Eryvarins F and G, two 3-phenoxychromones from the roots of erythrina variegata. Phytochemistry, 2003, 62(8), 1243-1246.
[http://dx.doi.org/10.1016/S0031-9422(02)00482-X] [PMID: 12648545]
[70]
Tanaka, H.; Oh-Uchi, T.; Etoh, H.; Sako, M.; Sato, M.; Fukai, T.; Tateishi, Y. An arylbenzofuran and four isoflavonoids from the roots of Erythrina poeppigiana. Phytochemistry, 2003, 63(5), 597-602.
[http://dx.doi.org/10.1016/S0031-9422(03)00184-5] [PMID: 12809721]
[71]
Tanaka, H.; Hirata, M.; Etoh, H.; Sato, M.; Murata, H.; Darnaedi, D.; Fukai, T. Four new isoflavonoids and a new 2-arylbenzofuran from the roots of Erythrina variegata. Heterocycles, 2003, 60, 2767-2773.
[http://dx.doi.org/10.3987/COM-03-9881]
[72]
Tanaka, H.; Sato, M.; Oh-Uchi, T.; Yamaguchi, R.; Etoh, H.; Shimizu, H.; Sako, M.; Takeuchi, H. Antibacterial properties of a new isoflavonoid from Erythrina poeppigiana against methicillin-resistant Staphylococcus aureus. Phytomedicine, 2004, 11(4), 331-337.
[http://dx.doi.org/10.1078/0944711041495137] [PMID: 15185847]
[73]
Tanaka, H.; Hattori, H.; Sato, M.; Yamaguchi, R.; Fukai, T.; Tanaka, T.; Sakai, E. New constituents from the roots of Erythrina x bidwillii. Heterocycles, 2007, 71, 1779-1785.
[http://dx.doi.org/10.3987/COM-07-11065]
[74]
Tanaka, H.; Hattori, H.; Oh-Uchi, T.; Sato, M.; Sako, M.; Tateishi, Y.; Rizwani, G.H. Three new isoflavanones from Erythrina costaricensis. Nat. Prod. Res., 2009, 23(12), 1089-1094.
[http://dx.doi.org/10.1080/14786410802292286] [PMID: 19662573]
[75]
Tanaka, H.; Atsumi, I.; Shirota, O.; Sekita, S.; Sakai, E.; Sato, M.; Murata, J.; Murata, H.; Darnaedi, D.; Chen, I.S. Three new constituents from the roots of Erythrina variegata and their antibacterial activity against methicillin-resistant Staphylococcus aureus. Chem. Biodivers., 2011, 8(3), 476-482.
[http://dx.doi.org/10.1002/cbdv.201000068] [PMID: 21404431]
[76]
Telikepalli, H.; Gollapudi, S.; Keshavarz-Shokri, A.; Velazquez, V.; Sandmann, R.; Veliz, E.; Madhavrt, K.J.; Mitscher, L. Isoflavonoids and a cinnamyl phenol from root extracts of Erythrina variegate. Phytochemistry, 1990, 29, 2005-2007.
[http://dx.doi.org/10.1016/0031-9422(90)85056-L]
[77]
Yenesew, A.; Midiwo, J.; Miessnert, M.; Heydenreich, M.; Petert, M. Two prenylated flavanones from stem bark of Erythrina burttii. Phytochemistry, 1998, 48, 1439-1443.
[http://dx.doi.org/10.1016/S0031-9422(97)00945-X]
[78]
Yenesew, A.; Midiwo, J.O.; Heydenreich, M.; Schanzenbach, D.; Peter, M.G.; Petert, M. Two isoflavanones from the stem bark of Erythrina sacleuxii. Phytochemistry, 2000, 55(5), 457-459.
[http://dx.doi.org/10.1016/S0031-9422(00)00349-6] [PMID: 11140607]
[79]
Yenesew, A.; Derese, S.; Midiwo, J.O.; Bii, C.C.; Heydenreich, M.; Peter, M.G. Antimicrobial flavonoids from the stem bark of Erythrina burttii. Fitoterapia, 2005, 76(5), 469-472.
[http://dx.doi.org/10.1016/j.fitote.2005.04.006] [PMID: 15967591]
[80]
Akter, K.; Barnes, E.C.; Loa-Kum-Cheung, W.L.; Yin, P.; Kichu, M.; Brophy, J.J.; Barrow, R.A.; Imchen, I.; Vemulpad, S.R.; Jamie, J.F. Antimicrobial and antioxidant activity and chemical characterisation of Erythrina stricta Roxb. (Fabaceae). J. Ethnopharmacol., 2016, 185, 171-181.
[http://dx.doi.org/10.1016/j.jep.2016.03.011] [PMID: 26969405]
[81]
Ali, M. Chemical constituents of Erythrina vogelii Hook., E. mildbraedii and E. sigmoidea Hua (Fabaceae). Ph.D. thesis, University of Karatchi, Pakistan. 2011.
[82]
Andayi, A.W.; Yenesew, A.; Derese, S.; Midiwo, J.O.; Gitu, P.M.; Jondiko, O.J.I.; Akala, H.; Liyala, P.; Wangui, J.; Waters, N.C.; Heydenreich, M.; Peter, M.G. Antiplasmodial flavonoids from Erythrina sacleuxii. Planta Med., 2006, 72(2), 187-189.
[http://dx.doi.org/10.1055/s-2005-873200] [PMID: 16491458]
[83]
Naglaa, S. Ashmawy, Mohamed L. Ashour, Michael Wink, Mohamed El-Shazly, Fang-Rong Chang, Noha Swilam, Ashraf B. Abdel-Naim, and Nahla Ayoub, Polyphenols from Erythrina crista-galli: Structures, Molecular Docking and Phytoestrogenic Activity. Molecules, 2016, 21, 726.
[http://dx.doi.org/10.3390/molecules21060726]
[84]
Chacha, M.; Bojase-Moleta, G.; Majinda, R.R. Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima. Phytochemistry, 2005, 66(1), 99-104.
[http://dx.doi.org/10.1016/j.phytochem.2004.10.013] [PMID: 15649516]
[85]
Chukwujekwu, J.C.; Van Heerden, F.R.; Van Staden, J. Antibacterial activity of flavonoids from the stem bark of Erythrina caffra thunb. Phytother. Res., 2011, 25(1), 46-48.
[http://dx.doi.org/10.1002/ptr.3159] [PMID: 20623615]
[86]
Desta, Z.Y.; Sewald, N.; Majinda, R.R. New flavonoids from the stem bark of Erythrina caffra Thunb. Nat. Prod. Res., 2014, 28(9), 667-673.
[http://dx.doi.org/10.1080/14786419.2014.895726] [PMID: 24665834]
[87]
Desta, Z.Y.; Sewald, N.; Majinda, R.R. Cytotoxic flavonoids from erythrina caffra Thunb. Bull. Chem. Soc. Ethiop., 2016, 30, 427-435.
[http://dx.doi.org/10.4314/bcse.v30i3.11]
[88]
Fomum, Z.; Ayafor, J.; Wandji, J. Erythrisenegalone, a prenylated-flavanone from Erythrina senegalensis. Phytochemistry, 1985, 24, 3075-3076.
[http://dx.doi.org/10.1016/0031-9422(85)80067-4]
[89]
Hikita, K.; Tanaka, H.; Murata, T.; Kato, K.; Hirata, M.; Sakai, T.; Kaneda, N. Phenolic constituents from stem bark of Erythrina poeppigiana and their inhibitory activity on human glyoxalase I. J. Nat. Med., 2014, 68(3), 636-642.
[http://dx.doi.org/10.1007/s11418-014-0834-z] [PMID: 24756815]
[90]
Huang, K.F.; Yen, Y.F. Three prenylated isoflavones from Erythrina variegate. J. Chin. Chem. Soc. (Taipei), 1996, 43, 515-518.
[http://dx.doi.org/10.1002/jccs.199600077]
[91]
Hussain, M.; Dastagir, M.; Billah, A.H.; Ismail, M. Alpinum isoflavone from erythrina stricta Roxb. Bol. Latinoam. Caribe Plantas Med. Aromat., 2011, 10, 88-90.
[92]
Jang, J.; Na, M.; Thuong, P.T.; Njamen, D.; Mbafor, J.T.; Fomum, Z.T.; Woo, E.R.; Oh, W.K. Prenylated flavonoids with PTP1B inhibitory activity from the root bark of erythrina mildbraedii. Chem. Pharm. Bull. (Tokyo), 2008, 56(1), 85-88.
[http://dx.doi.org/10.1248/cpb.56.85] [PMID: 18175982]
[93]
Kamusiime, H.; Pedersen, A.T.; Andersen, M.; Kiremire, B. Kaempferol 3-o-(2-O-β-D-glucopyranosyl-6-O-α-L-rhamnopy-ranosyl-β-D-glucopyranoside) from the African plant Erythrina abyssinica. Int. J. Pharmacol., 1996, 34, 370-373.
[94]
Khaomek, P.; Ichino, C.; Ishiyama, A.; Sekiguchi, H.; Namatame, M.; Ruangrungsi, N.; Saifah, E.; Kiyohara, H.; Otoguro, K.; Omura, S.; Yamada, H. In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca. J. Nat. Med., 2008, 62(2), 217-220.
[http://dx.doi.org/10.1007/s11418-007-0214-z] [PMID: 18404327]
[95]
Xiaoli, L.; Naili, W.; Sau, W.M.; Chen, A.S.; Xinsheng, Y. Four new isoflavonoids from the stem bark of Erythrina variegata. Chem. Pharm. Bull. (Tokyo), 2006, 54(4), 570-573.
[http://dx.doi.org/10.1248/cpb.54.570] [PMID: 16595969]
[96]
el-Masry, S.; Amer, M.E.; Abdel-Kader, M.S.; Zaatout, H.H. Prenylated flavonoids of Erythrina lysistemon grown in Egypt. Phytochemistry, 2002, 60(8), 783-787.
[http://dx.doi.org/10.1016/S0031-9422(02)00202-9] [PMID: 12150799]
[97]
Na, M.; Jang, J.; Njamen, D.; Mbafor, J.T.; Fomum, Z.T.; Kim, B.Y.; Oh, W.K.; Ahn, J.S. Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii. J. Nat. Prod., 2006, 69(11), 1572-1576.
[http://dx.doi.org/10.1021/np0601861] [PMID: 17125223]
[98]
Magne Nde, C.B.; Njamen, D.; Tanee Fomum, S.; Wandji, J.; Simpson, E.; Clyne, C.; Vollmer, G. In vitro estrogenic activity of two major compounds from the stem bark of Erythrina lysistemon (Fabaceae). Eur. J. Pharmacol., 2012, 674(2-3), 87-94.
[http://dx.doi.org/10.1016/j.ejphar.2011.10.031] [PMID: 22079771]
[99]
Nkengfack, A.E.; Sanson, D.R.; Tempesta, M.S.; Fomum, Z.T. Two new flavonoids from Erythrina eriotriocha. J. Nat. Prod., 1989, 52(2), 320-324.
[http://dx.doi.org/10.1021/np50062a017] [PMID: 2746257]
[100]
Nkengfack, A.E.; Sanson, D.R.; Tempesta, M.S. 8-Prenylluteone, a prenylated isoflavone from Erythrina eriotriocha. Phytochemistry, 1989, 28, 2522-2526.
[http://dx.doi.org/10.1016/S0031-9422(00)98025-7]
[101]
Nkengfack, A.E.; Fomum, Z.T.; Ubillas, R.; Sanson, D.R.; Tempesta, M.S. Extractives from Erythrina eriotriocha. J. Nat. Prod., 1990, 53(2), 509-512.
[http://dx.doi.org/10.1021/np50068a040] [PMID: 2380723]
[102]
Nkengfack, A.E.; Fomum, Z.T.; Ubillas, R.; Tempesta, M.S. A new prenylated isoflavone and triterpenoids from Erythrina eriotriocha. J. Nat. Prod., 1990, 53(6), 1552-1556.
[http://dx.doi.org/10.1021/np50072a024] [PMID: 2089122]
[103]
Nkengfack, A.E.; Vouffo, J.K.; Fomum, Z.T.; Dagne, E.; Sterner, O.; Browne, L.M.; Guijun, J. Further flavonoids from Erythrina species. Phytochemistry, 1993, 32, 1305-1311.
[http://dx.doi.org/10.1016/S0031-9422(00)95111-2]
[104]
Nkengfack, A.E.; Meyer, M.; Tempesta, M.S.; Fomum, Z.T. Auriculatin 4′-O-glucoside: A new prenylated isoflavone glycoside from Erythrina eriotricha. Planta Med., 1991, 57(5), 488-491.
[http://dx.doi.org/10.1055/s-2006-960179] [PMID: 17226186]
[105]
Nkengfack, A.E.; Waffo, A.K.; Azebaze, G.A.; Fomum, Z.T.; Meyer, M.; Bodo, B.; van Heerden, F.R. Indicanine A, a new 3-phenylcoumarin from root bark of Erythrina indica. J. Nat. Prod., 2000, 63(6), 855-856.
[http://dx.doi.org/10.1021/np990300y] [PMID: 10869220]
[106]
Nkengfack, A.E.; Azebaze, A.G.; Waffo, A.K.; Fomum, Z.T.; Meyer, M.; van Heerden, F.R. Cytotoxic isoflavones from Erythrina indica. Phytochemistry, 2001, 58(7), 1113-1120.
[http://dx.doi.org/10.1016/S0031-9422(01)00368-5] [PMID: 11730876]
[107]
Oh, W.; Lee, H.; Ahn, S.; Ahn, J. Mbafor, Wandji, J.; Fomum, Z.T.; Chang, H.; Kim, Y. Prenylated isoflavonoids from Erythrina senegalensis. Phytochemistry, 1999, 51, 1147-1150.
[http://dx.doi.org/10.1016/S0031-9422(99)00171-5]
[108]
Oh, W.K.; Lee, C.; Seo, J.H.; Chung, M.Y.; Cui, L.; Fomum, Z.T.; Kang, J.S.; Lee, H.S. Diacylglycerol acyltransferase-inhibitory compounds from Erythrina senegalensis. Arch. Pharm. Res., 2009, 32(1), 43-47.
[http://dx.doi.org/10.1007/s12272-009-1116-2] [PMID: 19183875]
[109]
Nguyen, P.H.; Na, M.; Dao, T.T.; Ndinteh, D.T.; Mbafor, J.T.; Park, J.; Cheong, H.; Oh, W.K. New stilbenoid with inhibitory activity on viral neuraminidases from Erythrina addisoniae. Bioorg. Med. Chem. Lett., 2010, 20(22), 6430-6434.
[http://dx.doi.org/10.1016/j.bmcl.2010.09.077] [PMID: 20934335]
[110]
Nguyen, P.H.; Sharma, G.; Dao, T.T.; Uddin, M.N.; Kang, K.W.; Ndinteh, D.T.; Mbafor, J.T.; Oh, W.K. New prenylated isoflavonoids as protein tyrosine phosphatase 1B (PTP1B) inhibitors from Erythrina addisoniae. Bioorg. Med. Chem., 2012, 20(21), 6459-6464.
[http://dx.doi.org/10.1016/j.bmc.2012.08.024] [PMID: 23022281]
[111]
Ombito, J.; Majinda, R.; Masesane, I.; Bojase, G.; Schüffler, A.; Opatz, T. Prenylated isoflavones from the stem bark of Erythrina sacleuxii. Phytochem. Lett., 2018, 26, 110-114.
[http://dx.doi.org/10.1016/j.phytol.2018.05.026]
[112]
Pérez, A.; Hassan, E.; Pecio, L.; Omer, E.; Kucinska, M.; Murias, M.; Stochmal, A. Triterpenoid saponins and C-glycosyl flavones from stem bark of Erythrina abyssinica Lam and their cytotoxic effects. Phytochem. Lett., 2015, 13, 59-67.
[http://dx.doi.org/10.1016/j.phytol.2015.05.013]
[113]
Pillay, C.C.; Jäger, A.K.; Mulholland, D.A.; van Staden, J. Cyclooxygenase inhibiting and anti-bacterial activities of South African Erythrina species. J. Ethnopharmacol., 2001, 74(3), 231-237.
[http://dx.doi.org/10.1016/S0378-8741(00)00366-4] [PMID: 11274823]
[114]
Queiroz, E.F.; Atindehou, K.K.; Terreaux, C.; Antus, S.; Hostettmann, K. Prenylated isoflavonoids from the root bark of Erythrina vogelii. J. Nat. Prod., 2002, 65(3), 403-406.
[http://dx.doi.org/10.1021/np0103867] [PMID: 11908991]
[115]
Rahman, M.; Rahman, M.; Kaisar, A.; Hossain, A.; Rashid, M. Bioactive isoflavones from Erythrina variegata L. Turk J. Pharm. Sci., 2010, 7, 21-28.
[116]
Sato, M.; Tanaka, H.; Tani, N.; Nagayama, M.; Yamaguchi, R. Different antibacterial actions of isoflavones isolated from Erythrina poeppigiana against methicillin-resistant Staphylococcus aureus. Lett. Appl. Microbiol., 2006, 43(3), 243-248.
[http://dx.doi.org/10.1111/j.1472-765X.2006.01963.x] [PMID: 16910926]
[117]
Tanaka, H.; Sudo, M.; Hirata, M.; Sako, M.; Sato, M.; Chen, I.S.; Fukai, T. Two new isoflavonoids and a new 2-arylbenzofuran from the roots of Erythrina variegate. Heterocycles, 2005, 65, 871-877.
[http://dx.doi.org/10.3987/COM-05-10321]
[118]
Taylor, R.B.; Corley, D.G.; Tempesta, M.S.; Fomum, Z.T.; Ayafor, J.F.; Wandji, J.; Ifeadike, P.N. 2,3-Dihydroauriculatin, a new prenylated isoflavanone from Erythrina senegalensis. Application of the selective inept technique. J. Nat. Prod., 1986, 49(4), 670-673.
[http://dx.doi.org/10.1021/np50046a019] [PMID: 3783163]
[119]
Tchokouaha, R.F.; Alexi, X.; Chosson, E.; Besson, T.; Skaltsounis, A-L.; Seguin, E.; Alexis, M.N.; Wandji, J. Erymildbraedin A and B, two novel cytotoxic dimethylpyrano-isoflavones from the stem bark of Erythrina mildbraedii: evaluation of their activity toward endocrine cancer cells. J. Enzyme Inhib. Med. Chem., 2010, 25(2), 228-233.
[http://dx.doi.org/10.3109/14756360903169972] [PMID: 19874114]
[120]
Kamdem Waffo, A.F.; Coombes, P.H.; Mulholland, D.A.; Nkengfack, A.E.; Fomum, Z.T. Flavones and isoflavones from the west African Fabaceae Erythrina vogelii. Phytochemistry, 2006, 67(5), 459-463.
[http://dx.doi.org/10.1016/j.phytochem.2005.09.022] [PMID: 16297941]
[121]
Waffo, A.K.; Azebaze, G.A.; Nkengfack, A.E.; Fomum, Z.T.; Meyer, M.; Bodo, B.; van Heerden, F.R. Indicanines B and C, two isoflavonoid derivatives from the root bark of Erythrina indica. Phytochemistry, 2000, 53(8), 981-985.
[http://dx.doi.org/10.1016/S0031-9422(99)00615-9] [PMID: 10820816]
[122]
Yenesew, A.; Irungu, B.; Derese, S.; Midiwo, J.O.; Heydenreich, M.; Peter, M.G. Two prenylated flavonoids from the stem bark of Erythrina burttii. Phytochemistry, 2003, 63(4), 445-448.
[http://dx.doi.org/10.1016/S0031-9422(03)00209-7] [PMID: 12770595]
[123]
Zarev, Y.; Foubert, K.; Lucia de Almeida, V.; Anthonissen, R.; Elgorashi, E.; Apers, S.; Ionkova, I.; Verschaeve, L.; Pieters, L. Antigenotoxic prenylated flavonoids from stem bark of Erythrina latissima. Phytochemistry, 2017, 141, 140-146.
[http://dx.doi.org/10.1016/j.phytochem.2017.06.003] [PMID: 28614730]
[124]
Wanjala, C.C.; Majinda, R.R. A new isoflavanone from the stem bark of Erythrina latissima. Fitoterapia, 2000, 71(4), 400-405.
[http://dx.doi.org/10.1016/S0367-326X(00)00142-8] [PMID: 10925011]
[125]
Wang, F.; Li, X.L.; Wei, G.Z.; Ren, F.C.; Liu, J.K. New isoflavonoids from Erythrina arborescens and structure revision of anagyroidisoflavone A. Nat. Prod. Bioprospect., 2013, 3, 238-242.
[http://dx.doi.org/10.1007/s13659-013-0062-3]
[126]
Yaya, A.; Feumba, R.; Emmanuel, T.; Tchinda, A.; Fredérich, M.; Oben, J.; Mbafor, J. Antioxidant Activity of compounds isolated from the root woods of Erythrina droogmansiana. Int. J. Pharm. Sci. Drug Res., 2014, 6, 160-163.
[127]
Yadava, R.N.; Reddy, K.I.S. A novel prenylated flavone glycoside from the seeds of Erythrina indica. Fitoterapia, 1999, 70, 357-360.
[http://dx.doi.org/10.1016/S0367-326X(99)00048-9]
[128]
Wandji, J.; Nkengfack, A.E.; Fomum, Z.T.; Ubillas, R.; Killday, K.B.; Tempesta, M.S. A new prenylated isoflavone and long chain esters from two Erythrina species. J. Nat. Prod., 1990, 53(6), 1425-1429.
[http://dx.doi.org/10.1021/np50072a004] [PMID: 2089116]
[129]
Wandji, J.; Fomum, Z.T.; Tillequin, F.; Seguin, E.; Koch, M. Two isoflavones from Erythrina senegalensis. Phytochemistry, 1994, 35, 245-248.
[http://dx.doi.org/10.1016/S0031-9422(00)90543-0]
[130]
Wandji, J.; Fomum, Z.T.; Tillequin, F.; Baudouin, G.; Koch, M. Epoxyisoflavones from Erythrina senegalensis. Phytochemistry, 1994, 35, 1573-1577.
[http://dx.doi.org/10.1016/S0031-9422(00)86896-X]
[131]
Wandji, J.; Awanchiri, S.; Fomum, Z.T.; Tillequin, F. Michel-Daniw1cz, S. Prenylated isoflavonoids from Erythrina sensegalensis. Phytochemistry, 1995, 38, 1309-1313.
[http://dx.doi.org/10.1016/0031-9422(94)00671-F]
[132]
Wandji, J.; Awanchiri, S.; Fomum, Z.T.; Tillequin, F.; Libot, F. Isoflavones and alkaloids from the stem bark and seeds of Erythrina senegalensis. Phytochemistry, 1995, 39, 677-681.
[http://dx.doi.org/10.1016/0031-9422(94)00779-S]
[133]
Ali, M.S.; Ali, M.I.; Ahmed, G.; Afza, N.; Lateef, M.; Iqbal, L.; Waffo, A.F.K.; Ahmed, Z. Potent antioxidant and lipoxygenase inhibitory flavanone and chalcone from Erythrina mildbraedii Harms (Fabaceae) of Cameroon. Z. Naturforsh, 2012, 67b, 98-102.
[http://dx.doi.org/10.1515/znb-2012-0116]
[134]
Bedane, K.G.; Kusari, S.; Eckelmann, D.; Masesane, I.B.; Spiteller, M.; Majinda, R.R. Erylivingstone A-C with antioxidant and antibacterial activities from Erythrina livingstoniana. Fitoterapia, 2015, 105, 113-118.
[http://dx.doi.org/10.1016/j.fitote.2015.06.016] [PMID: 26107527]
[135]
Bedane, K.; Masesane, I.; Majinda, R. New isoflavans from the root bark of Erythrina livingstoniana. Phytochem. Lett., 2016, 17, 55-58.
[http://dx.doi.org/10.1016/j.phytol.2016.07.023]
[136]
Cui, L.; Thuong, P.T.; Lee, H.S.; Ndinteh, D.T.; Mbafor, J.T.; Fomum, Z.T.; Oh, W.K. Flavanones from the stem bark of Erythrina abyssinica. Bioorg. Med. Chem., 2008, 16(24), 10356-10362.
[http://dx.doi.org/10.1016/j.bmc.2008.10.012] [PMID: 19008110]
[137]
Cui, L.; Lee, H.S.; Ndinteh, D.T.; Mbafor, J.T.; Kim, Y.H.; Le, T.V.T.; Nguyen, P.H.; Oh, W.K. New prenylated flavanones from Erythrina abyssinica with protein tyrosine phosphatase 1B (PTP1B) inhibitory activity. Planta Med., 2010, 76(7), 713-718.
[http://dx.doi.org/10.1055/s-0029-1240682] [PMID: 19960412]
[138]
Da-cunha, E.V.L.; Dias, C.; Filho, M.B.L.; Gray, A.I. Eryvellutinone, an isoflavanone from the stem bark of Erythrina vellutina. Phtyochemistry, 1996, 43, 1371-1373.
[http://dx.doi.org/10.1016/S0031-9422(96)00529-8]
[139]
Ichimaru, M.; Moriyasu, M.; Nishiyama, Y.; Kato, A. Structural elucidation of new flavanones isolated from Erythrina abyssinica. J. Nat. Prod., 1996, 59, 1113-1116.
[http://dx.doi.org/10.1021/np960440x]
[140]
Kumar, S.; Pathania, A.S.; Saxena, A.K.; Vishwakarma, R.A.; Ali, A.; Bhushan, S. The anticancer potential of flavonoids isolated from the stem bark of Erythrina suberosa through induction of apoptosis and inhibition of STAT signaling pathway in human leukemia HL-60 cells. Chem. Biol. Interact., 2013, 205(2), 128-137.
[http://dx.doi.org/10.1016/j.cbi.2013.06.020] [PMID: 23850732]
[141]
Iinuma, M.; Tanaka, T.; Mizuno, M.; Yamamoto, H.; Kobayashi, Y.; Yonemori, S. Phenolic constituents in Erythrina x bidwilli and their activity against oral microbial organisms. Chem. Pharm. Bull. (Tokyo), 1992, 40(10), 2749-2752.
[http://dx.doi.org/10.1248/cpb.40.2749] [PMID: 1464104]
[142]
Moriyasu, M.; Ichimaru, M.; Nishiyama, Y.; Kato, A.; Mathenge, S.G.; Juma, F.D.; Nganga, J.N. Minor flavanones from Erythrina abyssinica. J. Nat. Prod., 1998, 61(2), 185-188.
[http://dx.doi.org/10.1021/np9703048] [PMID: 9548845]
[143]
Nguyen, P.H.; Dao, T.T.; Kim, J.; Phong, T.; Ndinteh, D.T.; Mbafor, J.T.; Oh, W.K. New 5-deoxyflavonoids and their inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) activity. Bioorg. Med. Chem., 2011, 19(11), 3378-3383.
[http://dx.doi.org/10.1016/j.bmc.2011.04.037] [PMID: 21571537]
[144]
Wandji, J.; Fomum, Z.T. Erysenegalenseins B and C, two new prenylated isoflavanones from Erythrina senegalensis. J. Nat. Prod., 1995, 58, 105-108.
[http://dx.doi.org/10.1021/np50115a013]
[145]
Wätjen, W.; Suckow-Schnitker, A.K.; Rohrig, R.; Kulawik, A.; Addae-Kyereme, J.; Wright, C.W.; Passreiter, C.M. Prenylated flavonoid derivatives from the bark of Erythrina addisoniae. J. Nat. Prod., 2008, 71(4), 735-738.
[http://dx.doi.org/10.1021/np070417j] [PMID: 18302333]
[146]
Promsattha, R.; Tempesta, M.S.; Fomum, Z.T.; Ayafor, J.F.; Mbafor, J.T. Sigmoidin D: a new prenylated flavanone from Erythrina sigmoidea. J. Nat. Prod., 1986, 49(5), 932-933.
[http://dx.doi.org/10.1021/np50047a032] [PMID: 3819737]
[147]
Promsattha, R.; Tempesta, M.S.; Fomum, Z.T.; Mbafor, J.T. (-)-Sigmoidin E: A new prenylated flavonoid from Erythrina sigmoidea. J. Nat. Prod., 1988, 51(3), 611-613.
[http://dx.doi.org/10.1021/np50057a034] [PMID: 3404157]
[148]
Promsattha, R.; Mbafor, J.T.; Tempesta, M.S.; Fomum, Z.T. Sigmoidin F, a new prenylated flavonoid from Erythrina sigmoidea. J. Nat. Prod., 1989, 52(6), 1316-1318.
[http://dx.doi.org/10.1021/np50066a022] [PMID: 2614423]
[149]
Yenesew, A.; Induli, M.; Derese, S.; Midiwo, J.O.; Heydenreich, M.; Peter, M.G.; Akala, H.; Wangui, J.; Liyala, P.; Waters, N.C. Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica. Phytochemistry, 2004, 65(22), 3029-3032.
[http://dx.doi.org/10.1016/j.phytochem.2004.08.050] [PMID: 15504437]
[150]
Tanaka, H.; Hirata, M.; Etoh, H.; Sako, M.; Sato, M.; Murata, J.; Murata, H.; Darnaedi, D.; Fukai, T. Six new constituents from the roots of Erythrina variegata. Chem. Biodivers., 2004, 1(7), 1101-1108.
[http://dx.doi.org/10.1002/cbdv.200490082] [PMID: 17191901]
[151]
Yenesew, A.; Midiwo, J.O.; Guchu, S.M.; Heydenreich, M.; Peter, M.G.; Three, M. Three isoflav-3-enes and a 2-arylbenzofuran from the root bark of Erythrina burttii. Phytochemistry, 2002, 59(3), 337-341.
[http://dx.doi.org/10.1016/S0031-9422(01)00459-9] [PMID: 11830143]
[152]
Kouam, J.; Nkengfack, A.; Fomum, Z.T. Two new triterpenoid saponins from Erythrina sigmoidea. J. Nat. Prod., 1991, 54, 1288-1292.
[http://dx.doi.org/10.1021/np50077a008]
[153]
Kouam, J.; Meli, A.; Choudhary, M.; Fomum, Z.T. Sigmoiside F and propyloxyamyrin, two new triterpenoid derivatives from Erythrina sigmoidea (Fabaceae). Z. Naturforsch, 2008, 63b, 101-104.
[http://dx.doi.org/10.1515/znb-2008-0115]
[154]
Mbafor, J.; Ndom, J.; Fomum, Z.T. Triterpenoid saponins from Erythrina sigmoidea. Phytochemistry, 1997, 44, 1151-1155.
[http://dx.doi.org/10.1016/S0031-9422(96)00655-3]
[155]
Ndom, J.; Kouam, J.; Vardamides, J.; Wansi, J.; Kamdem, A.; Mbafor, J.; Fomum, Z.T. Constituents of Erythrina sigmoidea. Bull. Chem. Soc. Ethiop., 2001, 15, 151-156.
[156]
Liu, Q.; Yu, J.; Liao, X.; Zhang, P.; Chen, X. One-step separation of antioxidant compounds from Erythrina variegata by high speed counter-current chromatography. J. Chromatogr. Sci., 2015, 53(5), 730-735.
[http://dx.doi.org/10.1093/chromsci/bmu115] [PMID: 25209680]
[157]
Temesgen, A.; Tamir, A. Phytochemical investigation on the root of Erythrina abbyssinica (Korch). Intern. J. Modern Chem. Appl. Sci. (Basel), 2015, 2, 273-279.
[158]
Wanjala, C.C.; Juma, B.F.; Bojase, G.; Gashe, B.A.; Majinda, R.R.T. Erythrinaline alkaloids and antimicrobial flavonoids from Erythrina latissima. Planta Med., 2002, 68(7), 640-642.
[http://dx.doi.org/10.1055/s-2002-32891] [PMID: 12143000]
[159]
Tanaka, H.; Hirata, M.; Etoh, H.; Watanabe, N.; Shimizu, H.; Ahmad, M.; Terada, Y.; Fukai, T. Two diphenylpropan-1,2-diol syringates from the roots of Erythrina variegata. J. Nat. Prod., 2002, 65(12), 1933-1935.
[http://dx.doi.org/10.1021/np0201366] [PMID: 12502344]
[160]
El-Masry, S.; Hammoda, H.; Radwan, M.; Ross, S.; Zaatout, H. C-Flavonoidal glycosides from Erythrina caffra flowers. Nat. Prod. Sci., 2010, 16, 217-222.
[161]
Talla, E.; Njamen, D.; Mbafor, J.T.; Fomum, Z.T.; Kamanyi, A.; Mbanya, J.C.; Giner, R.M.; Recio, M.C.; Máñez, S.; Ríos, J.L. Warangalone, the isoflavonoid anti-inflammatory principle of Erythrina addisoniae stem bark. J. Nat. Prod., 2003, 66(6), 891-893.
[http://dx.doi.org/10.1021/np020599b] [PMID: 12828487]
[162]
Yenesew, A.; Midiwo, J.; Heydenreich, M.; Peter, M. Four isoflavones from the stem bark of Erythrina sacleuxii. Phytochemistry, 1998, 38, 136-138.
[http://dx.doi.org/10.1016/S0031-9422(97)00880-7]
[163]
Tanaka, H.; Hattori, H.; Oh-Uchi, T.; Sato, M.; Yamaguchi, R.; Sako, M.; Tateishi, Y. Two new isoflavanones from Erythrina costaricensis. J. Asian Nat. Prod. Res., 2008, 10(9-10), 983-987.
[http://dx.doi.org/10.1080/10286020802217598] [PMID: 19003619]
[164]
Tanaka, H.; Tanaka, T.; Hosoya, A.; Kitade, Y.; Etoh, H. Three isoflavanones from Erythrina orientalis. Phytochemistry, 1988, 48, 355-357.
[http://dx.doi.org/10.1016/S0031-9422(97)01012-1]
[165]
Iinuma, M.; Okawa, Y.; Tanaka, T. Three new cinnamylphenols in heartwood of Erythrina crista-galli. Phytochemistry, 1994, 37, 1153-1155.
[http://dx.doi.org/10.1016/S0031-9422(00)89548-5]
[166]
Selvam, C.; Jordan, B.C.; Prakash, S.; Mutisya, D.; Thilagavathi, R. Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties. Eur. J. Med. Chem., 2017, 128, 219-236.
[http://dx.doi.org/10.1016/j.ejmech.2017.01.023] [PMID: 28189086]
[167]
Ninh The. S. Son, N.T. A Review on the medicinal plant Dalbergia odorifera species: Phytochemistry and biological activity. Evid. Based Complement. Alternat. Med., 2017, 20177142370
[http://dx.doi.org/10.1155/2017/7142370] [PMID: 29348771]
[168]
Aksoz, B.E.; Ertan, R. Chemical and structural properties of chalcones I. FABAD. J. Pharm. Sci., 2011, 36, 223-242.
[169]
Chowdhury, A.R.; Mandal, S.; Mittra, B.; Sharma, S.; Mukhopadhyay, S.; Majumder, H.K. Betulinic acid, a potent inhibitor of eukaryotic topoisomerase I: identification of the inhibitory step, the major functional group responsible and development of more potent derivatives. Med. Sci. Monit., 2002, 8(7), BR254-BR265.
[PMID: 12118187]
[170]
Laszczyk, M.N. Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy. Planta Med., 2009, 75(15), 1549-1560.
[http://dx.doi.org/10.1055/s-0029-1186102] [PMID: 19742422]
[171]
Son, N.T. Secondary metabolites of genus Pandanus: An aspect of phytochemistry. Mini Rev. Org. Chem., 2019, 16, 689-710.
[http://dx.doi.org/10.2174/1570193X16666181206102740]
[172]
Lamarque, A.; Maestri, D.; Zygadlo, J.; Grosso, N. Volatile constituents from flowers of Acacia caven (Mol.) Mol. var. caven, Acacia aroma Gill. ex Hook., Erythrina crista-galli L. and Calliandra tweedii Benth. Flavour Fragrance J., 1998, 13, 266-268.
[http://dx.doi.org/10.1002/(SICI)1099-1026(1998070)13:4<266:AID-FFJ739>3.0.CO;2-5]
[173]
Samanta, T.; Laskar, S. Analysis of oil and fatty acids from the seeds of Erythrina variegata Linn. Biosci. Biotechnol. Res. Asia, 2013, 10, 433-437.
[http://dx.doi.org/10.13005/bbra/1149]
[174]
Samanta, T.; Laskar, S. Chemical investigation of Erythrina variegata Linn. Seed proteins. Food Chem., 2009, 114, 212-216.
[http://dx.doi.org/10.1016/j.foodchem.2008.09.040]

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