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Author(s): Enrico Garattini

Journal Name: Letters in Drug Design & Discovery

Volume 18 , Issue 2 , 2021

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VOLUME: 18
ISSUE: 2
Year: 2021
Page: [111 - 111]
Pages: 1
DOI: 10.2174/157018081802210224092046


Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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The Calibration Method of a stereo-Vision-Based Coordinates Measurement System via a Two-Axis Turntable--The Combination of Stereo Vision and Turntable

(E-pub Abstract Ahead of Print)

Author(s): Zimiao Zhang*, Zhiwu Wang, Shihai Zhang, Anqi Fu

Journal Name: Recent Patents on Mechanical Engineering

Abstract:

Background: Stereo-vision-based three-dimensional coordinates measurement technology has been widely applied in the military or civil fields. There are two problems that need to be solved. The first problem is that each camera internal parameters and the two cameras external parameters need to be calibrated. To increase the measurement range, usually the turntable is used with the stereo vision system together. The second problem is the calibration of the turntable.

Objective: The aim of the study is to construct and calibrate a stereo-vision-based coordinates measurement system via a two-axis turntable.

Methods: Considering that the internal parameters of each camera do not change during the measurement process and the complicated optimization process of one-step self-calibration, a two-step stereo vision calibration method is proposed. In the first step, we calibrate the internal parameters of each camera through a specially designed planar target with circular points. In the second step, on the basis of the calibrated results of the internal parameters, the two cameras external parameters are calibrated through a simple target which could be distributed in the measurement volume. For the calibration of the two-axis turntable, we calibrated the rotation axes of the turntable and the coordinates of points in the 3D space could be measured considering the non-orthogonality of the axes.

Results: Some experiments are provided to examine the calibration methods we proposed. They are the plane target measurement experiments, the standard ball center coordinates measurement experiments and target pose measurement experiments. Experiment results demonstrate the superiority of the calibration method we proposed.

Conclusion: We studied the calibration methods of the stereo-vision-based coordinates measurement system via a two-axis turntable. The experimental results show the measurement accuracy of our system is less than 0.1mm.

Keywords: Stereo-vision-based, coordinates measurement, two-step camera calibration, two-axis turntable, rotation axes calibration

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/2212797614666210223170442
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Fabrics Recommendation for Fashion Design by Using Fuzzy Logic and Rough Sets

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Author(s): Min Dong, Xianyi Zeng*, Ludovic Koehl, Junjie Zhang

Journal Name: Journal of Fuzzy Logic and Modeling in Engineering

Abstract:

Background: Fabric is one of the key and vital design factors in fashion design. However, selection of relevant fabrics is rather complex for designers and managers due to the complexity of criteria at different levels.

Introduction: In this paper, we propose a new fabric recommendation model in order to quickly realize fabric selection from non-technical fashion features only and predict fashion features from any fabric technical parameters. This approach is extremely significant for fashion designers who do not completely master fabric technical details. It is also very useful for fabric developers who have no knowledge on fashion markets and fashion consumers.

Method: The proposed fabric recommendation model has been built by exploiting designers’ professional knowledge and consumers’ preferences. Concretely, we first use fuzzy sets for formalizing and interpreting measured technical parameters and linguistic sensory properties of fabrics and then model the relation between the technical parameters and sensory properties by using rough sets. Next, we model the relation between fashion themes and sensory properties using fuzzy relations. By combining these two models, we establish a hybrid model characterizing the relation between fashion themes and technical parameters.

Result: The proposed model has been validated through a real fabric recommendation case for designer’s specific requirements. We can find that the proposed model is efficient since the averaged value of prediction errors is 8.57%, which does not exceed 10% (generally considered as allowable range of human perception error).

Conclusion: The proposed model will constitute one important component for establishing an intelligent recommender system for garment design, enabling to support innovations in textile/apparel industry in terms of mass customization and e-shopping.

Keywords: Fashion Design, Fashion Theme, Sensory Evaluation, Fuzzy Logic, Rough Sets

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/2666294901666210223165824
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Association of use of oral contraceptive pill (OCP) with expression pattern of different molecular subtypes of breast cancer

(E-pub Abstract Ahead of Print)

Author(s): Vitthal Khode, Sumangala Patil, Praveenkumar Shetty*, U S Dinesh, Komal Ruikar, Anil Bargale, Satish Patil

Journal Name: Current Women`s Health Reviews

Abstract:

Background: Triple negative breast carcinoma (TNBC) is a breast cancer subtype associated with high mortality and inadequate therapeutic options when compared to non TNBC. Clinical data indirectly suggests where Oral Contraceptive Pill (OCP) usage is high, prevalence of Estrogen Receptor+ (ER+) breast cancer is high and prevalence of TNBC is low. This has lead to our hypothesis that OCP use may increase risk of ER+ breast cancer and OCP use may reduce the risk of TNBC. We aimed at to comparing the prevalence and association of subtypes of breast cancer in OCP users with that of non-users among woman 30 to 60 years of age.

Methods: This hospital based observational study of three year duration included 155 subjects of primary invasive breast cancer who got admitted in our institution. The data was obtained for ER, PR, HER2 status, clinical classification and data in relation to demographic factors, reproductive history, and history of OCP use. 155 subjects were divided into two groups. Group-1 included 48 patients with history of OCP use and group-2 included 107 patients who have not used OCP. Data was analysed using SPSS-20.

Results: A significant increase in prevalence of molecular subtypes ER+, Progesterone Receptor+ (PR+) and Luminal B breast cancer in OCP users was observed compared to non-users. There was significant decrease in the age at the time of admission in ER+ cancer in OCP users (45.3 years) compared to non-users (52.2years). While age at the time of admission of Basal (TNBC) cancer patients in OCP users (53.1 years) was higher when compared to non-users (45.4years). Upon logistic regression the likelihood of ER+, PR+ and Luminal B in OCP users was 11%,10% and 13% less respectively with 1 year of higher age and the likelihood of TNBC in OCP users was 18% more and 8% less in non-users.

Conclusion: OCP use may be associated with increased prevalence of ER+, PR+ and Luminal B breast cancer. On the contrary OCP use is may be associated with delay in the progression of the TNBC.

Keywords: breast cancer, molecular subtype, oral contraceptive pill

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/1573404817666210223165259
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Epidemiological and Maternal Features of Maternal Mortality in the West of Iran: Hamadan, 2011-2019

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Author(s): Azam Ali Shirzad, Ebrahim Jalili, Fateme Shahbazi, Hasan Bahrami, Salman Khazaei, Samereh Ghelichkhani*

Journal Name: Current Women`s Health Reviews

Abstract:

Background: Maternal mortality is an important public health problem that is perceived as a sensitive indicator of the socioeconomic status and healthcare services.

Objective: This study aims to describe the epidemiological features of maternal mortality in Hamadan province in western Iran.

Methods: In this cross-sectional study, 50 maternal deaths that occurred in all hospitals and delivery places in the Hamadan province from March 2011 to January 2019 were studied for epidemiological features and history of pregnancy care of maternal death. Finally, the extracted data were analyzed using descriptive statistics in Stata software version 14.

Results: Our findings show that the mortality due to pregnancy and childbirth was 18.07 per 100,000 live birth. The majority of maternal death occurred in women aged 20-34 years living in urban areas who were mostly housewives. Kabudrahang and Razan towns had the highest maternal rate.

Conclusions: The present study revealed that maternal mortality is higher among women aged 20-34 years (mainly housewives) living in urban areas. Cesarean delivery, having a history of abortion, and gestational age under 37 weeks were other factors associated with maternal death. Therefore, it is suggested to direct the focus of pregnancy care and training programs on these high-risk groups.

Keywords: Maternal Mortality, Maternal death, Epidemiology, Iran

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/1573404817666210223164615
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Highlights on Important Medicinal Plants for the Menopause Syndrome

(E-pub Abstract Ahead of Print)

Author(s): Rafaele de A. Rodrigues, Aline de S. Ramos*, José Luiz P. Ferreira, Jefferson Rocha de A. Silva, Ana Clara B. Maria, Maíra Martins H. de Almeida, Ana Claudia F. Amaral*

Journal Name: Current Women`s Health Reviews

Abstract:

Background: A reduction in ovarian hormones, which is distinctive of menopause, often involves signs and symptoms that compromise the quality of life and health of women. The transient manifestations are changes in the menstrual cycle, vasomotor symptoms, neuropsychological symptoms, and genitourinary changes. In some cases, the hormonal changes can evolve to non-transitory manifestations, which include urinary incontinence, changes in metabolism, osteoporosis and cardiovascular diseases. Hormone replacement therapy is the treatment of choice to alleviate transient symptoms of menopause; however, there are many limitations, contraindications and situations in which the risks of adverse effects are high, such as coronary artery disease, stroke, venous thromboembolism, dementia, type 2 diabetes, and the increased incidence of breast cancer.

Objective: This work aims to highlight important medicinal plants for the treatment of the transient symptoms of menopause, with less side effects than traditional hormone replacement therapy.

Results: There is sufficient information regarding the efficacy and safety in the use of the following plant species in the treatment of transient symptoms of menopause: Actaea racemosa, Glycine max, Trifolium pratense, Salvia officinalis, Humulus lupulus, Panax ginseng, Vitex agnus-castus, and Trigonella foenum-graecum. Additionally, the search indicated the chemical classes related to the benefits of the selected species, adverse effects, and interactions with other drugs.

Keywords: Climacteric, Medicinal herbs, Hormone therapy, Phytoestrogen, Phytotherapy, Flavonoid, Triterpene, Steroids.

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DOI: 10.2174/1573404817666210223163845
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Fresh or Frozen Embryo Selection in Embryo Transfer: Live Birth Rates and Obstetric and Fetal/Neonatal Results

(E-pub Abstract Ahead of Print)

Author(s): Nurcan Kırca, Meryem Öngen*

Journal Name: Current Women`s Health Reviews

Abstract:

Assisted reproductive techniques used in the treatment of infertility have been promising methods for infertile individuals. Embryo selection and embryo transfer are an important part of assisting reproductive techniques. The selection of the embryo to be transferred is important for the implantation and clinical pregnancy success. In addition, whether to use a fresh embryo or frozen embryo for embryo transfer is a controversial issue. While the fresh embryo transfer technique is widely used, the frozen embryo transfer technique has become widespread. The main factor in choosing the method of freezing the embryos is to avoid the negative effects of controlled ovarian hyperstimulation on endometrial receptivity. Therefore, it is thought that the use of frozen embryos can improve pregnancy outcomes and reduce the risk of developing obstetric and perinatal problems. However, in the embryo freezing technique, there are problems such as the risk of developing degeneration in the embryo during freezing or thawing process and postponing the transfer. In addition, adverse conditions have been reported such as an increased risk of developing hypertensive disorders in the mother and macrosomia in the baby.

Keywords: Embryo transfer, fetal, fresh embryo, frozen embryo, neonatal, pregnancy

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/1573404817666210223163145
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Comparison of Amniotic Fluid Index and Single Deepest Vertical Pocket

(E-pub Abstract Ahead of Print)

Author(s): Roopa Padavagodu Shivananda*, Rekha Anbu, Shubha Rao, Nivedita Hegde, Anjali Suneel Mundkur, Shripad Hebbar

Journal Name: Current Women`s Health Reviews

Abstract:

Background: The best method of estimation of amniotic fluid volume is a matter of ongoing debate.

Objectives: To determine the perinatal & maternal outcomes in pregnant patients when the amniotic fluid volume was assessed by the amniotic fluid index (AFI) in comparison to the single deepest vertical pocket (SDVP).

Methods: We studied abnormal Cardiotocograph, meconium stained amniotic fluid, birth weight <2.5kg, Apgar score at 5 min <7, cord blood pH <7.2 & necessity for NICU admission as perinatal outcomes. Rate of diagnosis of oligohydramnios, induction of labor for oligohydramnios & mode of delivery were observed in maternal outcomes.

Results: Of the 697 pregnant patients recruited, 353 were in the AFI and 344 in the SDVP group. Perinatal outcomes were similar in both. In the AFI group, the number of women diagnosed with oligohydramnios was higher (p = 0.0333) & the rate of induction was also higher (p = 0.003378). Vaginal deliveries were more in the SDVP group. The Receiver Operating Characteristic curves showed statistically significant correlation with NICU stay, birth-weight, and mode of delivery. While an AFI of >5cm and SDVP of >1.9cm had good sensitivity in predicting babies with a birth weight of ≥ 2.5kg and avoiding NICU admissions, an AFI of > 5.8cm and an SDVP of > 1.9 cm had a sensitivity of around 80% in predicting successful vaginal deliveries.

Conclusion: The SDVP method has a slight edge over the AFI in terms of lower inductions and higher vaginal deliveries with comparable perinatal outcomes.

Keywords: AFI, SDVP, AFV, high-risk pregnancy, perinatal outcomes, maternal outcomes

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DOI: 10.2174/1573404817666210223162752
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Infertile Women's Perceptions Of Infertility: A Phenomenological Study Based On Metaphor Analysis

(E-pub Abstract Ahead of Print)

Author(s): Nurcan Kirca*, Aslı Sis Celik

Journal Name: Current Women`s Health Reviews

Abstract:

Backround: Infertility is an increasing health problem which affects 10-15% of couples across the world. Infertility can cause various psychosocial problems such as stress, anxiety, depression, loneliness, social isolation and stigmatization during the diagnosis and treatment process.

Objective: The study was designed to reveal what kinds of cognitive images (metaphors) women produce in defining infertility, why they produce them and whether the metaphors produced by them differ depending on their professional culture.

Methods: This study is a qualitative research carried out based on metaphor analysis in phenomenology design. The study was conducted with 15 participants. The data were collected by the researcher between May-July 2019.

Results: The metaphors revealed by participants on what infertility meant to them, according to their Professional culture, included dry and fruitless tree, a defective human, cube, cactus and rose, empty tin can, hope and snowdrop, orzo, parasite, national lottery ticket, stock market, figures, surprise egg, bird, a slowly filled lake, and a disease that is very difficult to treat for infertility.

Conclusion: Metaphors reflect the beliefs, values and norms of individuals. According to the findings, we can understand and comment infertile women’s perceptions on infertility and what the infertility means for them.

Keywords: Phenomenology, infertility, infertility perception, metaphor, nursing, professional culture

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/1573404817666210223162239
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