Bu4N⁺X^-(OAc)2 Assisted Oxidation and Halogenation of Anilines

Title:Bu4N⁺X^-(OAc)2 Assisted Oxidation and Halogenation of Anilines

Volume: 9 Issue: 5

Author(s): Hengchang Ma, Jinxia Wang, Ning An, Wenfeng Li, Lianhua Bai, Xiaojie Jia and Ziqiang Lei

Affiliation:

Keywords: Anilines, DMP, halogenations, oxidation, TBAB, iminoquinone, amino, pharmaceuticals, bromide, ammonium

Abstract: The collaborating partners of DMP and quaternary ammonium salt (TBAF, TBAC, TBAB, TBAI) emerged as powerful oxidation and halogenation reagents in the synthesis of structurally diversified iminoquinones were extensively investigated. The plausible mechanism concerned that the in-situ formed Bu4N⁺X^-(OAc)2 was the key intermediate, and further halogenation reaction occurred via electrophilic substitution process.

Cite this article as:

Ma Hengchang, Wang Jinxia, An Ning, Li Wenfeng, Bai Lianhua, Jia Xiaojie and Lei Ziqiang, Bu4N⁺X^-(OAc)2 Assisted Oxidation and Halogenation of Anilines, Letters in Organic Chemistry 2012; 9 (5) . https://dx.doi.org/10.2174/157017812801264728