Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety

Title:Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety

Volume: 9 Issue: 4

Author(s): Cheng-Xia Tan, Yan-Xia Shi, Jian-Quan Weng, Xing-Hai Liu, Bao-Ju Li, Wei-Guang Zhao

Affiliation:

Keywords: 1, 2, 4-triazole, Cyclopropane, Antifungal activity, Synthesis, Microwave irradiation, Ultrasonic irradiation

Abstract: A new series of 1,2,4-triazoles containing cyclopropane moiety were synthesized and characterized by 1H NMR and elemental analyses. The biological activities results showed that most of them exhibited significant fungicidal activity towards six test fungi. Among them, several showed superiority over the commercial fungicide during the present study.

Cite this article as:

Cheng-Xia Tan, Yan-Xia Shi, Jian-Quan Weng, Xing-Hai Liu, Bao-Ju Li, Wei-Guang Zhao , Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety, Letters in Drug Design & Discovery 2012; 9 (4) . https://dx.doi.org/10.2174/157018012799859954