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Current Pharmaceutical Biotechnology

Editor-in-Chief

ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Use of Macrocyclic Lactones in Cattle in the USA

Author(s): Lora R. Ballweber and Laurie A. Baeten

Volume 13, Issue 6, 2012

Page: [1061 - 1069] Pages: 9

DOI: 10.2174/138920112800399149

Price: $65

Abstract

The use of macrocyclic lactones has become the main stay for the treatment of endo- and ectoparasites in the cattle industry. Here we review those drugs that are currently approved for use in cattle in the United States. The general efficacy, tissue distribution and toxicity of each drug formulation are discussed. Included is a discussion regarding the current status for nematode anthelmintic resistance in cattle populations within the United States. Also provided is a current summary of ecological effects of macrocyclic lactones residues in manure.

Keywords: Anthelmintic, anthelmintic resistance, bovine, cattle, dung fauna, endectocide, macrocyclic lactones


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