Abstract
In this review, we will give a critical update of published studies using ultrasound for targeted therapeutic use. We will briefly discuss the interaction mechanisms and their effects in non-invasive delivery of therapeutic agents. Moreover, the mechanisms by which ultrasonic contrast agents facilitate the delivery of drugs and genes into tissue will be discussed, together with recent applications and perspectives of targeted-microbubbles in cardiovascular medicine.
Keywords: Therapeutic ultrasound, targeted contrast agents, cardiovascular disease, contrast echocardiography
Current Drug Discovery Technologies
Title: Ultrasound Techniques for Drug Delivery in Cardiovascular Medicine
Volume: 5 Issue: 4
Author(s): Luigi Landini, Maria Filomena Santarelli, Linda Landini and Vincenzo Positano
Affiliation:
Keywords: Therapeutic ultrasound, targeted contrast agents, cardiovascular disease, contrast echocardiography
Abstract: In this review, we will give a critical update of published studies using ultrasound for targeted therapeutic use. We will briefly discuss the interaction mechanisms and their effects in non-invasive delivery of therapeutic agents. Moreover, the mechanisms by which ultrasonic contrast agents facilitate the delivery of drugs and genes into tissue will be discussed, together with recent applications and perspectives of targeted-microbubbles in cardiovascular medicine.
Export Options
About this article
Cite this article as:
Landini Luigi, Santarelli Filomena Maria, Landini Linda and Positano Vincenzo, Ultrasound Techniques for Drug Delivery in Cardiovascular Medicine, Current Drug Discovery Technologies 2008; 5 (4) . https://dx.doi.org/10.2174/157016308786733573
DOI https://dx.doi.org/10.2174/157016308786733573 |
Print ISSN 1570-1638 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6220 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Microparticles in Health and Disease: Small Mediators, Large Role?
Current Vascular Pharmacology Metformin and Energy Metabolism in Breast Cancer: From Insulin Physiology to Tumour-initiating Stem Cells
Current Molecular Medicine Role of PI3K/AKT/mTOR Pathway Associated Oxidative Stress and Cardiac Dysfunction in Takotsubo Syndrome
Current Neurovascular Research Editorial [Hot Topic : Current Practice and trends in echocardiography in Critical Care, Anesthesiology and Emergency Medicine (Guest Editor: Paulo Marcelino)]
Current Cardiology Reviews NAD+, Sirtuins, and Cardiovascular Disease
Current Pharmaceutical Design Circulating Biomarkers of Collagen Metabolism and Prognosis of Heart Failure with Reduced or Mid-Range Ejection Fraction
Current Pharmaceutical Design Potential Roles of MyomiRs in Cardiac Development and Related Diseases
Current Cardiology Reviews Anabolic Androgenic Steroids and Intracellular Calcium Signaling: A Mini Review on Mechanisms and Physiological Implications
Mini-Reviews in Medicinal Chemistry Lipoprotein Subfractions, Uric Acid and Cardiovascular Risk in End-Stage Renal Disease (ESRD) Patients
Current Vascular Pharmacology Adverse Bioeffects of Ultrasound Contrast Agents Used in Echocardiography: True Safety Issue or “Much Ado About Nothing”?
Current Vascular Pharmacology Kinins and Cardiovascular Diseases
Current Pharmaceutical Design Sarcolemmal K<sub>ATP</sub> Channel Modulators and Cardiac Arrhythmias
Current Medicinal Chemistry The Complex Biology of FOXO
Current Drug Targets A Brief History of ‘Lone’ Atrial Fibrillation: From ‘A Peculiar Pulse Irregularity’ to a Modern Public Health Concern
Current Pharmaceutical Design PDE5 Inhibitor Treatment Options for Urologic and Non-Urologic Indications: 2012 Update
Current Pharmaceutical Design Human Urotensin II Promotes Hypertension and Atherosclerotic Cardiovascular Diseases
Current Medicinal Chemistry Parathyroid Hormone and Heart Failure: Novel Biomarker Strategy
Endocrine, Metabolic & Immune Disorders - Drug Targets Matricellular Proteins in Myocardial Infarction
Current Cardiology Reviews Novel Carriers for Coenzyme Q10 Delivery
Current Drug Delivery Use of Peripheral Blood Stem Cells in Tissue Engineering
Current Tissue Engineering (Discontinued)