Abstract
In this review, we will give a critical update of published studies using ultrasound for targeted therapeutic use. We will briefly discuss the interaction mechanisms and their effects in non-invasive delivery of therapeutic agents. Moreover, the mechanisms by which ultrasonic contrast agents facilitate the delivery of drugs and genes into tissue will be discussed, together with recent applications and perspectives of targeted-microbubbles in cardiovascular medicine.
Keywords: Therapeutic ultrasound, targeted contrast agents, cardiovascular disease, contrast echocardiography
Current Drug Discovery Technologies
Title: Ultrasound Techniques for Drug Delivery in Cardiovascular Medicine
Volume: 5 Issue: 4
Author(s): Luigi Landini, Maria Filomena Santarelli, Linda Landini and Vincenzo Positano
Affiliation:
Keywords: Therapeutic ultrasound, targeted contrast agents, cardiovascular disease, contrast echocardiography
Abstract: In this review, we will give a critical update of published studies using ultrasound for targeted therapeutic use. We will briefly discuss the interaction mechanisms and their effects in non-invasive delivery of therapeutic agents. Moreover, the mechanisms by which ultrasonic contrast agents facilitate the delivery of drugs and genes into tissue will be discussed, together with recent applications and perspectives of targeted-microbubbles in cardiovascular medicine.
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Cite this article as:
Landini Luigi, Santarelli Filomena Maria, Landini Linda and Positano Vincenzo, Ultrasound Techniques for Drug Delivery in Cardiovascular Medicine, Current Drug Discovery Technologies 2008; 5 (4) . https://dx.doi.org/10.2174/157016308786733573
DOI https://dx.doi.org/10.2174/157016308786733573 |
Print ISSN 1570-1638 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6220 |
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