Pharmacotherapeutic Approach to Prevent or Treat Chronic Allograft Nephropathy

Title: Pharmacotherapeutic Approach to Prevent or Treat Chronic Allograft Nephropathy

Volume: 2 Issue: 2

Author(s): E. M. Scholten, J. W. de Fijter and L. C. Paul

Affiliation:

Keywords: Pharmacotherapeutic, Chronic Allograft, Nephropathy, Cyclosporin, Mycophenolate Mofetil, Tacrolimus

Abstract: In the current paper we will review the evidence that drug therapy may be of value to prevent or treat chronic allograft nephropathy. We will review the immunosuppressive therapy and non-immune therapies in use to treat risk factors associated with chronic allograft nephropathy and evaluate their efficacy with respect to long term outcome as well as their effect on markers of long-term survival. In the last part of this review, we will indicate possible benefits of new approaches being explored but most of these data are obtained in in vitro test systems and rodent models.

Cite this article as:

Scholten M. E., de Fijter W. J. and Paul C. L., Pharmacotherapeutic Approach to Prevent or Treat Chronic Allograft Nephropathy, Current Drug Targets - Cardiovascular & Hematological Disorders 2002; 2 (2) . https://dx.doi.org/10.2174/1568006023337484