Abstract
The battle between human and the Human immunodeficiency virus (HIV) is on, with both of them rapidly improving their attacking and defense strategies. Many therapeutic agents for HIV infection have been designed and developed, However there are various aspects, like novel targets against HIV, which are yet to be unfolded with a goal of designing and developing novel drug molecules against HIV. This article reviews the current status and innovative new options for antiretroviral therapy for HIV and also discusses the various mechanisms of action for each class of drugs, and the problems yet to be solved with respect to HIV as a target for improvised treatment against AIDS.
Keywords: antiretrovira, Lentivirus, HIV, host cellular target, life cycle, treatment, nucleoside, reverse transcriptase, Candida albicans, protease, integrase, carbohydrate binding proteins, Griffithsin, synthesis, inhibitors
Mini-Reviews in Medicinal Chemistry
Title: Targeting Strategies for Human Immunodeficiency Virus: A Combinatorial Approach
Volume: 12 Issue: 3
Author(s): S. K. Saxena, A. Gupta, K. Bhagyashree, R. Saxena, N. Arora, A. K. Banerjee, A. K. Tripathi, M. J.N. Chandrasekar, N. Gandhi and M. P.N. Nair
Affiliation:
Keywords: antiretrovira, Lentivirus, HIV, host cellular target, life cycle, treatment, nucleoside, reverse transcriptase, Candida albicans, protease, integrase, carbohydrate binding proteins, Griffithsin, synthesis, inhibitors
Abstract: The battle between human and the Human immunodeficiency virus (HIV) is on, with both of them rapidly improving their attacking and defense strategies. Many therapeutic agents for HIV infection have been designed and developed, However there are various aspects, like novel targets against HIV, which are yet to be unfolded with a goal of designing and developing novel drug molecules against HIV. This article reviews the current status and innovative new options for antiretroviral therapy for HIV and also discusses the various mechanisms of action for each class of drugs, and the problems yet to be solved with respect to HIV as a target for improvised treatment against AIDS.
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Cite this article as:
K. Saxena S., Gupta A., Bhagyashree K., Saxena R., Arora N., K. Banerjee A., K. Tripathi A., J.N. Chandrasekar M., Gandhi N. and P.N. Nair M., Targeting Strategies for Human Immunodeficiency Virus: A Combinatorial Approach, Mini-Reviews in Medicinal Chemistry 2012; 12 (3) . https://dx.doi.org/10.2174/1389557511209030236
DOI https://dx.doi.org/10.2174/1389557511209030236 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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