Recent Developments on Carbon-Carbon Bond Forming Reactions in Water

Devdutt      Chaturvedi; Nabin      C. Barua

Abstract

In recent years water has emerged as a versatile solvent for the synthesis of a variety of organic compounds employing plethora of organic reactions. Water as a solvent is not only inexpensive and environmentally benign, but also exhibits new reactivity. The types of organic reactions in water are broad including pericyclic reactions, reactions of carbanion equivalents, reactions of carbocation equivalents, reactions of radicals and carbenes, transition metal catalysis, oxidations-reductions, etc. In the present review, we are focusing on some recent and most important carbon-carbon bond forming reactions utilizing water as a reaction media published from the year 2005 onwards.

Keywords: Carbon-carbon bond forming reactions, green reaction media, water, carbanion equivalents, transition metal catalysis, oxidations-reductions, pollution, Claisen rearrangements, organometallic reactions, Michael-type condensations, Sonogashira Coupling Reaction, stereoselective reactions