Abstract
Benzothiazoles and its derivatives are an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antitumor, antimicrobial, antidiabetic, anticonvulsant and anti-inflammatory. These different biological applications for benzothiazole compounds have motivated new efforts in search for novel derivatives with improved biological activity and diverse applications in pharmaceutical industry. Owing to the importance of this system, the aim of this review is to highlight aspects reported on the chemistry and biological activity of benzothiazoles during the past few years (2000-2010).
Keywords: 1,3-Benzothiazoles, synthesis, biological activity, drugs, heterocyclic compounds, antidiabetic, anticonvulsant, anti-inflammatory, antimicrobial activity, antitumor activity
Mini-Reviews in Organic Chemistry
Title: Chemistry and Biological Activities of 1,3-Benzothiazoles
Volume: 9 Issue: 1
Author(s): Victor Facchinetti, Raisa da R. Reis, Claudia R.B. Gomes and Thatyana R.A. Vasconcelos
Affiliation:
Keywords: 1,3-Benzothiazoles, synthesis, biological activity, drugs, heterocyclic compounds, antidiabetic, anticonvulsant, anti-inflammatory, antimicrobial activity, antitumor activity
Abstract: Benzothiazoles and its derivatives are an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antitumor, antimicrobial, antidiabetic, anticonvulsant and anti-inflammatory. These different biological applications for benzothiazole compounds have motivated new efforts in search for novel derivatives with improved biological activity and diverse applications in pharmaceutical industry. Owing to the importance of this system, the aim of this review is to highlight aspects reported on the chemistry and biological activity of benzothiazoles during the past few years (2000-2010).
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Facchinetti Victor, da R. Reis Raisa, R.B. Gomes Claudia and R.A. Vasconcelos Thatyana, Chemistry and Biological Activities of 1,3-Benzothiazoles, Mini-Reviews in Organic Chemistry 2012; 9 (1) . https://dx.doi.org/10.2174/157019312799079929
DOI https://dx.doi.org/10.2174/157019312799079929 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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