Abstract
The filamentous fungus ‘ Monascus’ has been used as a natural food coloring and folk medicine in East Asia for centuries. Several bioactive substances produced by Monascus species have been isolated and identified. Recent studies demonstrated their mode of action in vitro and effectiveness in vivo, and their utilization for health foods and medicine has advanced. This mini review will introduce the physiological functions and safety of bioorganic chemicals produced by Monascus species.
Keywords: Monascus, γ-aminobutyric acid, polyketide metabolites, dimerumic acid, hypertension, hypercholesterolemia, ANGIOTENSIN CONVERTING ENZYME, monacolins, citrinin, B-conglicinin
Mini-Reviews in Organic Chemistry
Title: Bioorganic Compounds Produced by the Fungus Monascus and their Use in Health Sciences and Medicine
Volume: 9 Issue: 1
Author(s): Megumi Kuba-Miyara and Masaaki Yasuda
Affiliation:
Keywords: Monascus, γ-aminobutyric acid, polyketide metabolites, dimerumic acid, hypertension, hypercholesterolemia, ANGIOTENSIN CONVERTING ENZYME, monacolins, citrinin, B-conglicinin
Abstract: The filamentous fungus ‘ Monascus’ has been used as a natural food coloring and folk medicine in East Asia for centuries. Several bioactive substances produced by Monascus species have been isolated and identified. Recent studies demonstrated their mode of action in vitro and effectiveness in vivo, and their utilization for health foods and medicine has advanced. This mini review will introduce the physiological functions and safety of bioorganic chemicals produced by Monascus species.
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Cite this article as:
Kuba-Miyara Megumi and Yasuda Masaaki, Bioorganic Compounds Produced by the Fungus Monascus and their Use in Health Sciences and Medicine, Mini-Reviews in Organic Chemistry 2012; 9 (1) . https://dx.doi.org/10.2174/157019312799080071
DOI https://dx.doi.org/10.2174/157019312799080071 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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