Synthesis and Antibacterial Activity of 6-Substituted Anacardic Acid Derivatives

Subhakara      Reddy Nallamilli; Ravi      Kumar V; Himabindu      V; B.      Ram; Srinivas      Rao Aalapati

Abstract

New anacardic acid derivatives (5a -5s) were prepared from commercially available anacardic acid and tested for Gram positive and Gram negative bacteria. Most compounds were found to be active compared to ampicillin drug.

Keywords: Ampicillin, Anacardic acid derivatives, Antibacterial activity, Cashew Nut Shell Liquid, Ozonolysis, Synthesis, staphylococci, beta-lactam antibiotics, Vancomycin, Cashew nut shell liquid (CNSL), nonisoprenoid, Pseudomonas arzenous, MRSA, anti-bacterial activity, IR spectra

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Letters in Drug Design & Discovery

Title: Synthesis and Antibacterial Activity of 6-Substituted Anacardic Acid Derivatives

Volume: 8 Issue: 10

Author(s): Subhakara Reddy Nallamilli, Ravi Kumar V, Himabindu V, B. Ram and Srinivas Rao Aalapati

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Abstract: New anacardic acid derivatives (5a -5s) were prepared from commercially available anacardic acid and tested for Gram positive and Gram negative bacteria. Most compounds were found to be active compared to ampicillin drug.

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Reddy Nallamilli Subhakara, Kumar V Ravi, V Himabindu, Ram B. and Rao Aalapati Srinivas, Synthesis and Antibacterial Activity of 6-Substituted Anacardic Acid Derivatives, Letters in Drug Design & Discovery 2011; 8 (10) . https://dx.doi.org/10.2174/157018011797655278