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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Development of Sugar-Based Materials for Biological Devices

Author(s): Yuji Mikata and Shigenobu Yano

Volume 12, Issue 3, 2012

Page: [145 - 157] Pages: 13

DOI: 10.2174/156802612799079017

Price: $65

Abstract

Recent progresses of our group dealing with newly developed sugar-based ligands and their metal complexes have been reviewed. Carbohydrate moiety affects on the stereochemistry around the metal center and controls the biological activity of the complex.

Keywords: Carbohydrates, metal, porphyrin, nucleic acids, biological activity of the complex, macrocycles, β-lactams, β-C-glycosylation, bioactive molecules, metal complexes, peptide synthesis, anomeric oxygen atoms, peptide-based drug candidates, apical atoms


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