Abstract
Reciprocal interactions between wakefulness and sleep substantially influence human brain function in both states of vigilance. On the one hand, there is evidence that regionally-specialized brain activity during wakefulness is modulated by the interaction between a local use-dependent buildup of homeostatic sleep pressure and circadian signals. On the other hand, brain activity during sleep, although mainly constrained by genuine sleep oscillations, shows wakedependent regionally-specific modulations, which are involved in the dissipation of local homeostatic sleep pressure and memory consolidation.
Keywords: Sleep, slow waves, spindles, REM sleep, circadian rhythms, cognition, memory, neuroimaging, circadian signals, memory consolidation, regional modifications of brain, homeostatic regulation, core components, posterior cingulate cortices
Current Topics in Medicinal Chemistry
Title: Reciprocal Interactions Between Wakefulness and Sleep Influence Global and Regional Brain Activity
Volume: 11 Issue: 19
Author(s): Vincenzo Muto, Laura Mascetti, Luca Matarazzo, Caroline Kusse, Ariane Foret, Anahita Shaffii-Le Bourdiec, Gilles Vandewalle, Derk Jan Dijk and Pierre Maquet
Affiliation:
Keywords: Sleep, slow waves, spindles, REM sleep, circadian rhythms, cognition, memory, neuroimaging, circadian signals, memory consolidation, regional modifications of brain, homeostatic regulation, core components, posterior cingulate cortices
Abstract: Reciprocal interactions between wakefulness and sleep substantially influence human brain function in both states of vigilance. On the one hand, there is evidence that regionally-specialized brain activity during wakefulness is modulated by the interaction between a local use-dependent buildup of homeostatic sleep pressure and circadian signals. On the other hand, brain activity during sleep, although mainly constrained by genuine sleep oscillations, shows wakedependent regionally-specific modulations, which are involved in the dissipation of local homeostatic sleep pressure and memory consolidation.
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Cite this article as:
Muto Vincenzo, Mascetti Laura, Matarazzo Luca, Kusse Caroline, Foret Ariane, Shaffii-Le Bourdiec Anahita, Vandewalle Gilles, Jan Dijk Derk and Maquet Pierre, Reciprocal Interactions Between Wakefulness and Sleep Influence Global and Regional Brain Activity, Current Topics in Medicinal Chemistry 2011; 11 (19) . https://dx.doi.org/10.2174/156802611797470358
DOI https://dx.doi.org/10.2174/156802611797470358 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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