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Recent Patents on Cardiovascular Drug Discovery

Editor-in-Chief

ISSN (Print): 2212-3962
ISSN (Online): 1574-8901

Relation Between Sleep Quality and Physical Activity in Chronic Heart Failure Patients

Author(s): Kazuhiro P. Izawa, Satoshi Watanabe, Koichiro Oka, Koji Hiraki, Yuji Morio, Yusuke Kasahara, Naoya Takeichi, Takae Tsukamoto, Naohiko Osada, Kazuto Omiya and Haruo Makuuchi

Volume 6, Issue 3, 2011

Page: [161 - 167] Pages: 7

DOI: 10.2174/157489011797377004

Price: $65

Abstract

To determine self-reported sleep quality-related differences in physical activity (PA) and health-related quality of life (HRQOL) and target values of PA for high-quality sleep in chronic heart failure (CHF) outpatients, 149 CHF outpatients (mean age 58 years) were divided into two groups by sleep-quality level determined via self-reported questionnaire: shallow sleep (SS) group (n = 77) and deep sleep (DS) group (n = 72). Steps were assessed by electronic pedometer, HRQOL was assessed with the Short Form 36 (SF-36) survey, and data were compared between groups. PA resulting in high-quality sleep was determined by receiver-operating characteristics curves. All SF-36 subscale scores except that of bodily pain were significantly decreased in the SS versus DS group. A cutoff value of 5723.6 steps/day and 156.4 Kcal/day for 1 week were determined as target values for PA. Sleep quality may affect PA and HRQOL, and attaining target values of PA may improve sleep quality and HRQOL of CHF outpatients. Patents relevant to heart failure are also discussed in this article.

Keywords: Chronic heart failure, health-related quality of life, physical activity, self-reported sleep quality, treatment, HRQOL, Statistical Analysis, ROC Curves, HRQOL Assessment, Quality Questionnaire

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