Abstract
The development of technetium based diagnostic imaging agents continues to remain a high impact area in nuclear medicine research. In particular, the single photon emitting radionuclide 99mTc comprises the majority of diagnostic imaging scans performed daily at hospitals and clinics. While research with 99mTc has been active for several decades, this review focuses on the overview of recent developments and current trends surrounding 99mTc applications. Discussion includes the fundamental design of 99mTc complexes, new labeling methodologies, and development of molecular probes for the next generation of in vivo diagnostic imaging agents.
Keywords: Technetium, complexes, radiopharmaceuticals, nuclear medicine, SPECT, Probe, Molecular Imaging, TC CHEMISTRY, PEPTIDE BASED Tc AGENTS, NANOPARTICLES
Current Organic Synthesis
Title: Recent Advances in the Probe Development of Technetium-99m Molecular Imaging Agents
Volume: 8 Issue: 4
Author(s): Paul D. Benny and Adam L. Moore
Affiliation:
Keywords: Technetium, complexes, radiopharmaceuticals, nuclear medicine, SPECT, Probe, Molecular Imaging, TC CHEMISTRY, PEPTIDE BASED Tc AGENTS, NANOPARTICLES
Abstract: The development of technetium based diagnostic imaging agents continues to remain a high impact area in nuclear medicine research. In particular, the single photon emitting radionuclide 99mTc comprises the majority of diagnostic imaging scans performed daily at hospitals and clinics. While research with 99mTc has been active for several decades, this review focuses on the overview of recent developments and current trends surrounding 99mTc applications. Discussion includes the fundamental design of 99mTc complexes, new labeling methodologies, and development of molecular probes for the next generation of in vivo diagnostic imaging agents.
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Cite this article as:
D. Benny Paul and L. Moore Adam, Recent Advances in the Probe Development of Technetium-99m Molecular Imaging Agents, Current Organic Synthesis 2011; 8 (4) . https://dx.doi.org/10.2174/157017911796117214
DOI https://dx.doi.org/10.2174/157017911796117214 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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