One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound

Title: One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound

Volume: 8 Issue: 4

Author(s): Chuansheng Shen, Yumin Zhang, Yuanming Gan, Tianqi Zhao and Qiang Gu

Affiliation:

Keywords: Ultrasound, aldoximes, 1,3-dipolar cycloaddition, nitrile oxide, isoxazole, one-pot synthesis, pharmacophores, hydroxylamine, herbicide, phenylisoxazol

Abstract: An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5- yl)methanol derivatives has been developed. (3-Phenylisoxazol-5-yl)-methanol derivatives with biological and pharmaceutical property have been synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.

Cite this article as:

Shen Chuansheng, Zhang Yumin, Gan Yuanming, Zhao Tianqi and Gu Qiang, One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371467