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Current Vascular Pharmacology

Editor-in-Chief

ISSN (Print): 1570-1611
ISSN (Online): 1875-6212

Pleiotropic Effects of ARB in Diabetes Mellitus

Author(s): Shu-ichi Saitoh and Yasuchika Takeishi

Volume 9, Issue 2, 2011

Page: [136 - 144] Pages: 9

DOI: 10.2174/157016111794519363

Price: $65

Abstract

Evidence accumulated to date indicates that inhibition of the renin-angiotensin system with angiotensin receptor blockers (ARB) may prevent new-onset of diabetes. ARB is also used for the prevention of occurrence and progression of complications in diabetes and diabetic nephropathy. From the results of recent large-scale clinical studies, ARB is considered as a first choice drug in hypertensive patients with diabetes. In this review article, we focus on the effects of ARB on progression and prevention against diabetes as a metabolic-improving agent.

Keywords: Metabolism, prevention, nephropathy, retinopathy


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