Relationship Between Virulence Factors and Outcome of Ventilator-Associated Pneumonia Related to Pseudomonas aeruginosa

Title: Relationship Between Virulence Factors and Outcome of Ventilator-Associated Pneumonia Related to Pseudomonas aeruginosa

Volume: 6 Issue: 1

Author(s): Lorenzo Berra, Ulrich Schmidt and Jeanine Wiener-Kronish

Affiliation:

Keywords: Ventilator-associated pneumonia, Pseudomonas aeruginosa, Pseudomonas aeruginosa bacterial cell surface virulence factors, Pseudomonas aeruginosa secreted virulence factors, Pseudomonas aeruginosa type III secretion system, Pseudomonas aeruginosa quorum-sensing

Abstract: Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative, aerobic, rod-shaped and polar-flagella bacterium with unipolar motility, and an opportunistic pathogen responsible for ventilator-acquired pneumonia (VAP). VAP due to P. aeruginosa is usually multidrug-resistant and associated with severe infection and increased mortality. The large genome and the high level of gene regulation may explain part of the significant virulence and of the prominent adaptability to different environments of this pathogen. In this review, we discussed the potential relationship between some of the virulent factors of P. aeruginosa and outcome of patient with VAP.

Cite this article as:

Berra Lorenzo, Schmidt Ulrich and Wiener-Kronish Jeanine, Relationship Between Virulence Factors and Outcome of Ventilator-Associated Pneumonia Related to Pseudomonas aeruginosa, Current Respiratory Medicine Reviews 2010; 6 (1) . https://dx.doi.org/10.2174/157339810790820458