Abstract
A protein domain interaction prediction program was complied using C++ to predict whether a query protein could interact with other hub proteins. It is indicated that the proteins interacting with AATF (Apoptosis-Antagonizing Transcription Factor) possess a common conservative pattern: I-x(0,1)-E-x(2)-[A/E/N/T]-x-[E/K]. Our method is attempted to integrate the characteristics of protein interaction network with the simplest building blocks-conservative patterns.
Keywords: AD associated protein interaction network, signal pathway, conservative interaction pattern
Protein & Peptide Letters
Title: A Novel Approach to Predict Protein-Protein Interactions Related to Alzheimers Disease Based on Complex Network
Volume: 17 Issue: 3
Author(s): Jie Yang and Xiong-Fei Jiang
Affiliation:
Keywords: AD associated protein interaction network, signal pathway, conservative interaction pattern
Abstract: A protein domain interaction prediction program was complied using C++ to predict whether a query protein could interact with other hub proteins. It is indicated that the proteins interacting with AATF (Apoptosis-Antagonizing Transcription Factor) possess a common conservative pattern: I-x(0,1)-E-x(2)-[A/E/N/T]-x-[E/K]. Our method is attempted to integrate the characteristics of protein interaction network with the simplest building blocks-conservative patterns.
Export Options
About this article
Cite this article as:
Yang Jie and Jiang Xiong-Fei, A Novel Approach to Predict Protein-Protein Interactions Related to Alzheimers Disease Based on Complex Network, Protein & Peptide Letters 2010; 17 (3) . https://dx.doi.org/10.2174/092986610790780323
DOI https://dx.doi.org/10.2174/092986610790780323 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects
Current Pharmaceutical Design Physiological Mechanisms of Action of Incretin and Insulin in Regulating Skeletal Muscle Metabolism
Current Diabetes Reviews FDA-approved Drugs Selected Using Virtual Screening Bind Specifically to G-quadruplex DNA
Current Pharmaceutical Design The Relaxin Peptide Family – Structure, Function and Clinical Applications
Protein & Peptide Letters Serum Amyloid Beta Peptides in Patients with Dementia and Age-Matched Non-Demented Controls as Detected by Surface-Enhanced Laser Desorption Ionisation-Time of Flight Mass Spectrometry (SELDI-TOF MS)
Current Clinical Pharmacology Analysis of the Drug Release Profiles from Formulations Based on Micro and Nano Systems
Current Analytical Chemistry Commentary: Death Associated Protein Kinase 1: A Perp in Cerebral Ischemia
CNS & Neurological Disorders - Drug Targets Dimeric and Hybrid Anti-Alzheimer Drug Candidates
Current Medicinal Chemistry Impact of Online Teaching on Students’ Education and Health in India during the Pandemic of COVID-19
Coronaviruses Peripheral Mononuclear Cell Rejuvenation for Senescence Surveillance in Alzheimer Disease
Current Pharmaceutical Design Depression and Quality of Life in Patients with Diabetes: A Systematic Review from the European Depression in Diabetes (EDID) Research Consortium
Current Diabetes Reviews Group-Analysis of Resting-State fMRI Based on Bayesian Network: A Comparison of Three Virtual-Typical-Subject Methods
Neuroscience and Biomedical Engineering (Discontinued) Clinical and Therapeutic Challenges when Psychiatric Disorders Occur in Neurological Diseases: A Narrative Review
Current Psychiatry Research and Reviews Structure, Pharmacology and Therapeutic Prospects of Family C G-Protein Coupled Receptors
Current Drug Targets The Nervous System as a Critical Regulator of Immune Responses Underlying Allergy
Current Pharmaceutical Design Tau Phosphorylation and Aggregation as a Therapeutic Target in Tauopathies
CNS & Neurological Disorders - Drug Targets Sedation and Analgesia in Pediatric Intensive Care
Current Drug Targets Genomic Linkage Between Alzheimer's Disease and Type 2 Diabetes
CNS & Neurological Disorders - Drug Targets Cervical Cancer: Are There Potential New Targets? An Update on Preclinical and Clinical Results
Current Drug Targets Human Cognition Assessment in Drug Research
Current Pharmaceutical Design