Abstract
The intent of this article is to review recent literature on ribosome inactivating proteins (RIPs) including isolation and characterization of new RIPs, studies on the crystal structures and mechanisms of actions of RIPs, the use of saporin-based neurotoxins to selectively lesion cholinergic neurons in neuroscience research, and the use of RIP-based conjugates and immunotoxins in anticancer therapy.
Current Protein & Peptide Science
Title: Recent Progress in Research on Ribosome Inactivating Proteins
Volume: 11 Issue: 1
Author(s): T. B. Ng, Jack Ho Wong and Hexiang Wang
Affiliation:
Abstract: The intent of this article is to review recent literature on ribosome inactivating proteins (RIPs) including isolation and characterization of new RIPs, studies on the crystal structures and mechanisms of actions of RIPs, the use of saporin-based neurotoxins to selectively lesion cholinergic neurons in neuroscience research, and the use of RIP-based conjugates and immunotoxins in anticancer therapy.
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Cite this article as:
Ng B. T., Wong Ho Jack and Wang Hexiang, Recent Progress in Research on Ribosome Inactivating Proteins, Current Protein & Peptide Science 2010; 11 (1) . https://dx.doi.org/10.2174/138920310790274662
DOI https://dx.doi.org/10.2174/138920310790274662 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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