Abstract
Carbon nanotubes are widely used for biomedical applications as intracellular transporters of biomolecules, due to their high propensity to cross cell membranes. In this review we summarize the recent advancement in the functionalization of carbon nanotubes, focusing particular attention on the chemistry involved in the preparation of nanovectors for drug delivery systems, and on the physical and chemical properties that affect cellular up-take and biodistribution phenomena.
Keywords: Carbon nanotubes, nanovectors, biomedical applications, functionalization, drug delivery, gene delivery, cellular up-take, biodistribution
Mini-Reviews in Medicinal Chemistry
Title: Chemically Functionalized Carbon Nanotubes: Emerging Vectors for Cell Therapy
Volume: 9 Issue: 11
Author(s): Gianni Ciofani and Vittoria Raffa
Affiliation:
Keywords: Carbon nanotubes, nanovectors, biomedical applications, functionalization, drug delivery, gene delivery, cellular up-take, biodistribution
Abstract: Carbon nanotubes are widely used for biomedical applications as intracellular transporters of biomolecules, due to their high propensity to cross cell membranes. In this review we summarize the recent advancement in the functionalization of carbon nanotubes, focusing particular attention on the chemistry involved in the preparation of nanovectors for drug delivery systems, and on the physical and chemical properties that affect cellular up-take and biodistribution phenomena.
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Ciofani Gianni and Raffa Vittoria, Chemically Functionalized Carbon Nanotubes: Emerging Vectors for Cell Therapy, Mini-Reviews in Medicinal Chemistry 2009; 9 (11) . https://dx.doi.org/10.2174/138955709789878132
DOI https://dx.doi.org/10.2174/138955709789878132 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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