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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

Author(s): M. T. Murakami, R. M. Kini and R. K. Arni

Volume 16, Issue 12, 2009

Page: [1473 - 1477] Pages: 5

DOI: 10.2174/092986609789839304

Price: $65

Abstract

Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 A resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered α-neurotoxin possessing a positively charged AChR-binding site.

Keywords: Bucain, crystal structure, Bungarus candidus, three-finger α-neurotoxin


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