Abstract
Hypertension is a major contributor to vascular morbidity and mortality. Endocrine hypertension (EH) refers to secondary hypertension caused by specific endocrine abnormalities. The significance of EH is that the identification of the underlying disorder and its management may lead to partial or complete normalization of blood pressure. When EH is suspected thorough investigation with biochemical and imaging testing are necessary to establish or exclude mineralocorticoid, catecholamine, glucocorticoid, thyroid, parathyroid or growth hormone disorders as well as rare hereditary syndromes. In addition, it is important to differentiate benign from malignant tumors. The present review provides an update on the pathophysiology and clinical presentation of EH. We also discuss the diagnostic work-ups and therapeutic strategies.
Keywords: Endocrine hypertension, primary aldosteronism, pheochromocytoma, Cushing's syndrome
Current Vascular Pharmacology
Title: Endocrine Hypertension: Diagnosis and Management of a Complex Clinical Entity
Volume: 8 Issue: 5
Author(s): Panagiotis Anagnostis, Asterios Karagiannis, Konstantinos Tziomalos, Vasilios G. Athyros, Marina Kita and Dimitri P. Mikhailidis
Affiliation:
Keywords: Endocrine hypertension, primary aldosteronism, pheochromocytoma, Cushing's syndrome
Abstract: Hypertension is a major contributor to vascular morbidity and mortality. Endocrine hypertension (EH) refers to secondary hypertension caused by specific endocrine abnormalities. The significance of EH is that the identification of the underlying disorder and its management may lead to partial or complete normalization of blood pressure. When EH is suspected thorough investigation with biochemical and imaging testing are necessary to establish or exclude mineralocorticoid, catecholamine, glucocorticoid, thyroid, parathyroid or growth hormone disorders as well as rare hereditary syndromes. In addition, it is important to differentiate benign from malignant tumors. The present review provides an update on the pathophysiology and clinical presentation of EH. We also discuss the diagnostic work-ups and therapeutic strategies.
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Cite this article as:
Anagnostis Panagiotis, Karagiannis Asterios, Tziomalos Konstantinos, G. Athyros Vasilios, Kita Marina and P. Mikhailidis Dimitri, Endocrine Hypertension: Diagnosis and Management of a Complex Clinical Entity, Current Vascular Pharmacology 2010; 8 (5) . https://dx.doi.org/10.2174/157016110792006996
DOI https://dx.doi.org/10.2174/157016110792006996 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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