Abstract
Structure and function of synthetic amino acids with side chain metal complexes have particular importance for extending our understanding of organometallic compounds under physiological conditions and mimic protein folding and stabilization. Chemists are now designing biomimetic organo-metallic amino acids that can form both secondary and tertiary structures. An overview of the design and synthesis of non-proteinogenic amino acids containing metal ions in the side chain is discussed.
Keywords: Amino acid analogues, side chain metal complex, synthesis, structure
Current Organic Synthesis
Title: Developments in the Synthesis of Organometallic Amino Acids and Analogues
Volume: 7 Issue: 3
Author(s): Poulami Jana, Sibaprasad Maity and Debasish Haldar
Affiliation:
Keywords: Amino acid analogues, side chain metal complex, synthesis, structure
Abstract: Structure and function of synthetic amino acids with side chain metal complexes have particular importance for extending our understanding of organometallic compounds under physiological conditions and mimic protein folding and stabilization. Chemists are now designing biomimetic organo-metallic amino acids that can form both secondary and tertiary structures. An overview of the design and synthesis of non-proteinogenic amino acids containing metal ions in the side chain is discussed.
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Cite this article as:
Jana Poulami, Maity Sibaprasad and Haldar Debasish, Developments in the Synthesis of Organometallic Amino Acids and Analogues, Current Organic Synthesis 2010; 7 (3) . https://dx.doi.org/10.2174/157017910791162995
DOI https://dx.doi.org/10.2174/157017910791162995 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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