Abstract
This article reviews the characteristics of the main fluoroquinolones used in dentistry (ciprofloxacin, levofloxacin and moxifloxacin), including pharmacokinetic/ pharmacodynamic parameters, susceptibility profiles of oral bacteria and clinical trials on their efficacy in dental practice. It seems that some of these antibiotics might represent a safe alternative in patients with allergy, intolerance, or lack of response to beta-lactams.
Keywords: Antimicrobial susceptibility, ciprofloxacin, fluoroquinolones, focal infection, levofloxacin, moxifloxacin, oral infection, oral pathogens
Mini-Reviews in Medicinal Chemistry
Title: Efficacy of Fluoroquinolones Against Pathogenic Oral Bacteria
Volume: 9 Issue: 10
Author(s): V. Nunez Otero, J. Limeres Posse, I. Tomas Carmona and P. Diz Dios
Affiliation:
Keywords: Antimicrobial susceptibility, ciprofloxacin, fluoroquinolones, focal infection, levofloxacin, moxifloxacin, oral infection, oral pathogens
Abstract: This article reviews the characteristics of the main fluoroquinolones used in dentistry (ciprofloxacin, levofloxacin and moxifloxacin), including pharmacokinetic/ pharmacodynamic parameters, susceptibility profiles of oral bacteria and clinical trials on their efficacy in dental practice. It seems that some of these antibiotics might represent a safe alternative in patients with allergy, intolerance, or lack of response to beta-lactams.
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Cite this article as:
Otero Nunez V., Posse Limeres J., Carmona Tomas I. and Dios Diz P., Efficacy of Fluoroquinolones Against Pathogenic Oral Bacteria, Mini-Reviews in Medicinal Chemistry 2009; 9 (10) . https://dx.doi.org/10.2174/138955709789055243
DOI https://dx.doi.org/10.2174/138955709789055243 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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