Abstract
Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.
Keywords: Quantum dots, in vivo imaging, cancer
Recent Patents on Anti-Cancer Drug Discovery
Title: Use of the Semiconductor Nanotechnologies “Quantum Dots” for in vivo Cancer Imaging
Volume: 4 Issue: 3
Author(s): Monica Ciarlo, Patrizia Russo, Alfredo Cesario, Sara Ramella, Gabriella Baio, Carlo E. Neumaier and Laura Paleari
Affiliation:
Keywords: Quantum dots, in vivo imaging, cancer
Abstract: Non-invasive in vivo imaging offers great potential to facilitate translational drug development research at the animal testing phase. The emerging luminescent nanoparticles or quantum dots provide a new type of biological agents that can improve these applications. The advantages of luminescent nanoparticles for biological applications include their high quantum yield, color availability, good photo-stability, large surface-to-volume ratio, surface functionality, and small size. These properties could improve the sensitivity of biological detection and imaging by at least 10- to 100-fold and make them an exceptional tool for live-cell imaging. In this review patents on applications of semiconductor quantum dots for in vivo imaging are discussed.
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Ciarlo Monica, Russo Patrizia, Cesario Alfredo, Ramella Sara, Baio Gabriella, Neumaier E. Carlo and Paleari Laura, Use of the Semiconductor Nanotechnologies “Quantum Dots” for in vivo Cancer Imaging, Recent Patents on Anti-Cancer Drug Discovery 2009; 4 (3) . https://dx.doi.org/10.2174/157489209789206841
DOI https://dx.doi.org/10.2174/157489209789206841 |
Print ISSN 1574-8928 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3970 |
Call for Papers in Thematic Issues
Novel anti-cancer drugs in photoimmunotherapy management: from bench to translational research
In recent years, traditional cancer treatments, such as surgery, chemotherapy, and radiation treatment, etc., may damage the pathological tissue and normal cells. The ideal tumor treatment should be noninvasive, eliminating the primary tumor, making the body produce systemic tumor-specific immunity, eliminating metastases, and having less /no side effects. Recent Patents ...read more
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